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Serum HBV RNA: a promising biomarker for blood product safety screening and enhanced diagnostic efficiency in chronic hepatitis B virus infection.

作者信息

Yu Sulan, Guo Yanjuan, Zhang Chunxiao

机构信息

Central Blood Station of Lianyungang, Lianyungang, China.

出版信息

Front Public Health. 2023 Aug 31;11:1248878. doi: 10.3389/fpubh.2023.1248878. eCollection 2023.

DOI:10.3389/fpubh.2023.1248878
PMID:37719720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10501715/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a9/10501715/ec094392718f/fpubh-11-1248878-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a9/10501715/ec094392718f/fpubh-11-1248878-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a9/10501715/ec094392718f/fpubh-11-1248878-g0001.jpg

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本文引用的文献

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Guidance on treatment endpoints and study design for clinical trials aiming to achieve cure in chronic hepatitis B and D: Report from the 2022 AASLD-EASL HBV-HDV Treatment Endpoints Conference.旨在实现慢性乙型肝炎和丁型肝炎治愈的临床试验治疗终点和研究设计指南:2022 年美国肝病研究学会-欧洲肝脏研究学会乙型肝炎-丁型肝炎治疗终点会议报告。
J Hepatol. 2023 Nov;79(5):1254-1269. doi: 10.1016/j.jhep.2023.06.002. Epub 2023 Jun 21.
2
A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook.乙型肝炎病毒血清标志物的研究路线图:现状与展望。
Nat Rev Gastroenterol Hepatol. 2022 Nov;19(11):727-745. doi: 10.1038/s41575-022-00649-z. Epub 2022 Jul 20.
3
A standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients.
一种用于定量检测慢性乙型肝炎患者血清 HBV RNA 的标准化检测方法。
Emerg Microbes Infect. 2022 Dec;11(1):775-785. doi: 10.1080/22221751.2022.2045874.
4
Characteristic of HBV nucleic acid amplification testing yields from blood donors in China.中国献血者乙型肝炎病毒核酸检测结果的特征。
BMC Infect Dis. 2021 Jul 30;21(1):714. doi: 10.1186/s12879-021-06468-y.
5
Comparison of HBV RNA and Hepatitis B Core Related Antigen With Conventional HBV Markers Among Untreated Adults With Chronic Hepatitis B in North America.北美未经治疗的慢性乙型肝炎成年患者中 HBV RNA 和乙型肝炎核心相关抗原与常规 HBV 标志物的比较。
Hepatology. 2021 Nov;74(5):2395-2409. doi: 10.1002/hep.32018. Epub 2021 Sep 9.
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Residual HBV DNA and pgRNA viraemia is associated with hepatocellular carcinoma in chronic hepatitis B patients on antiviral therapy.抗病毒治疗的慢性乙型肝炎患者中,HBV DNA 和 pgRNA 病毒血症残留与肝细胞癌相关。
J Gastroenterol. 2021 May;56(5):479-488. doi: 10.1007/s00535-021-01780-5. Epub 2021 Mar 27.
7
Yin-Yang 1 and HBx protein activate HBV transcription by mediating the spatial interaction of cccDNA minichromosome with cellular chromosome 19p13.11.阴阳 1 和 HBx 蛋白通过介导 cccDNA 微染色体与细胞染色体 19p13.11 的空间相互作用来激活 HBV 转录。
Emerg Microbes Infect. 2020 Dec;9(1):2455-2464. doi: 10.1080/22221751.2020.1840311.
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Severe Acute Respiratory Syndrome Coronavirus 2 RNA Detected in Blood Donations.血标本中检测到严重急性呼吸综合征冠状病毒 2 型 RNA。
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