马凡综合征患者接受个性化主动脉根部支撑后的妊娠情况。
Pregnancy following personalised aortic root support in Marfan syndrome.
作者信息
Coroyannakis Christina, Tome Maite, Watt-Coote Ingrid, Cauldwell Matthew
机构信息
St George's University Hospitals NHS Foundation Trust, London, UK.
出版信息
Obstet Med. 2023 Sep;16(3):200-202. doi: 10.1177/1753495X221078447. Epub 2022 Feb 11.
Abstract
Marfan syndrome (MFS) is linked with adverse pregnancy events, one of the most significant being aortic dissection. We present a case of a woman with MFS with prior aortic root dilatation who opted for a Personalised External Aortic Root Support (PEARS). To date, she is only the fifth woman to have had this valve-sparing procedure prior to pregnancy. We outline her care in a tertiary centre with multidisciplinary expertise, from preconception through to the postpartum period.
摘要
马凡综合征（MFS）与不良妊娠事件有关，其中最严重的一种是主动脉夹层。我们报告一例患有马凡综合征且既往有主动脉根部扩张的女性病例，该患者选择了个性化体外主动脉根部支撑（PEARS）。迄今为止，她是第五位在怀孕前接受这种保留瓣膜手术的女性。我们概述了她在一家拥有多学科专业知识的三级中心从孕前到产后的治疗情况。
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本文引用的文献
1
PEARS procedure and the difficulty to provide evidence for its benefits.
Eur Heart J. 2020 Nov 7;41(42):4086-4088. doi: 10.1093/eurheartj/ehaa596.
2
Pregnancy in congenital heart disease: risk prediction and counselling.
Heart. 2020 Dec;106(23):1853-1861. doi: 10.1136/heartjnl-2019-314702. Epub 2020 Jul 1.
3
Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart Association.
Circulation. 2020 Jun 9;141(23):e884-e903. doi: 10.1161/CIR.0000000000000772. Epub 2020 May 4.
4
The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome: A single-center experience.
Sci Rep. 2019 Aug 19;9(1):12021. doi: 10.1038/s41598-019-48572-9.
5
Maternal and fetal outcomes in pregnancies complicated by Marfan syndrome.
Heart. 2019 Nov;105(22):1725-1731. doi: 10.1136/heartjnl-2019-314817. Epub 2019 May 25.
6
Pregnancy after Aortic Root Replacement in Marfan's Syndrome: A Case Series and Review of the Literature.
AJP Rep. 2018 Oct;8(4):e234-e240. doi: 10.1055/s-0038-1675347. Epub 2018 Oct 18.
7
Birth weight in pregnancies complicated by maternal heart disease.
Heart. 2019 Mar;105(5):391-398. doi: 10.1136/heartjnl-2018-313551. Epub 2018 Sep 21.
8
External Aortic Root Support to Prevent Aortic Dilatation in Patients With Marfan Syndrome.
J Am Coll Cardiol. 2018 Sep 4;72(10):1095-1105. doi: 10.1016/j.jacc.2018.06.053.
9
2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy.
Eur Heart J. 2018 Sep 7;39(34):3165-3241. doi: 10.1093/eurheartj/ehy340.
10
Pregnancy and Marfan syndrome.
Ann Cardiothorac Surg. 2017 Nov;6(6):642-653. doi: 10.21037/acs.2017.10.07.
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