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通过增强免疫力作为非药物干预措施应对新冠疫情:一项重大的公共卫生挑战。

Coping with the COVID-19 pandemic by strengthening immunity as a nonpharmaceutical intervention: A major public health challenge.

作者信息

Uddin Nizam, Acter Thamina, Rashid Md Harun-Ar, Chowdhury Akibul Islam, Jahan Effat Ara

机构信息

Department of Nutrition and Food Engineering, Faculty of Allied Health Science Daffodil International University Dhaka Bangladesh.

Department of Mathematical and Physical Sciences East West University Dhaka Bangladesh.

出版信息

Health Sci Rep. 2023 Sep 13;6(9):e1562. doi: 10.1002/hsr2.1562. eCollection 2023 Sep.

DOI:10.1002/hsr2.1562
PMID:37720166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10500053/
Abstract

BACKGROUND AND AIMS

The global Coronavirus-2 outbreak has emerged as a significant threat to majority of individuals around the world. The most effective solution for addressing this viral outbreak is through vaccination. Simultaneously, the virus's mutation capabilities pose a potential risk to the effectiveness of both vaccines and, in certain instances, newly developed drugs. Conversely, the human body's immune system exhibits a robust ability to combat viral outbreaks with substantial confidence, as evidenced by the ratio of fatalities to affected individuals worldwide. Hence, an alternative strategy to mitigate this pandemic could involve enhancing the immune system's resilience.

METHODS

The research objective of the review is to acquire a comprehensive understanding of the role of inflammation and immunity in COVID-19. The pertinent literature concerning immune system functions, the impact of inflammation against viruses like SARS-CoV-2, and the connection between nutritional interventions, inflammation, and immunity was systematically explored.

RESULTS

Enhancing immune function involves mitigating the impact of key factors that negatively influence the immune response. Strengthening the immune system against emerging diseases can be achieved through nonpharmaceutical measures such as maintaining a balanced nutrition, engaging in regular exercise, ensuring adequate sleep, and managing stress.

CONCLUSION

This review aims to convey the significance of and provide recommendations for immune-strengthening strategies amidst the ongoing COVID-19 pandemic.

摘要

背景与目的

全球新型冠状病毒2的爆发已成为对全球大多数人的重大威胁。应对这一病毒爆发的最有效解决方案是接种疫苗。同时,病毒的变异能力对疫苗以及某些新研发药物的有效性构成潜在风险。相反,从全球死亡人数与感染人数的比例可以看出,人体免疫系统具有强大的能力,能够信心十足地对抗病毒爆发。因此,减轻这场大流行的另一种策略可能是增强免疫系统的恢复力。

方法

本综述的研究目的是全面了解炎症和免疫在2019冠状病毒病中的作用。系统地探讨了有关免疫系统功能、炎症对严重急性呼吸综合征冠状病毒2等病毒的影响以及营养干预、炎症和免疫之间联系的相关文献。

结果

增强免疫功能包括减轻对免疫反应产生负面影响的关键因素的影响。通过保持营养均衡、定期锻炼、保证充足睡眠和管理压力等非药物措施,可以增强免疫系统抵御新出现疾病的能力。

结论

本综述旨在传达在当前2019冠状病毒病大流行期间增强免疫策略的重要性并提供相关建议。

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