McDougall Emma, Breen Lauren J, Nowak Anna K, Dhillon Haryana M, Halkett Georgia K B
Faculty of Health Sciences, Curtin School of Nursing/Curtin Health Innovation Research Institute (CHIRI), Curtin University, Perth, WA, Australia.
Curtin School of Population Health, Curtin University, Perth, WA, Australia.
Neurooncol Pract. 2023 Jun 13;10(5):408-417. doi: 10.1093/nop/npad031. eCollection 2023 Oct.
The objective of this scoping review was to describe the intervention characteristics and effectiveness of psychosocial interventions aimed at managing personality and behavior changes in people with brain tumors. A secondary objective was to explore if these interventions had an impact on outcomes for carers. Personality and behavior changes considered included aggression, apathy, paranoia, disinhibition, and emotional lability.
This review was conducted following the Joanna Briggs Institute methodology for scoping reviews and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for scoping reviews. Searches were conducted in PsycINFO, CINAHL, Medline (Ovid), and Scopus. We synthesized studies published from 1996 to 2022 that evaluated interventions to manage brain tumor related personality and behavioral changes in adults. A data extraction tool were used based on the Joanna Briggs Institute template. Results are presented in a summary table and a narrative synthesis was conducted.
Three thousand and five hundred and ninety-four records were screened. Title and abstract screening resulted in 29 potentially eligible studies. Full screening excluded 24 articles and 5 interventions met the inclusion criteria. The interventions were diverse in duration, delivery modality, setting, and participation (eg, the patient individually or patient and carer). The interventions reported improvements in the targeted personality and behavior change symptoms for patients with primary brain tumors. Four studies included a measure of personality and behavior change symptoms and two studies included a measure of outcomes for carers and reported improvements in carer knowledge and a reduction in carer distress. All studies sampled fewer than 100 participants. Studies had limited follow-up data and different tools were used to assess the presence and nature of personality and behavior changes.
There is a dearth of psychosocial interventions to support patients and their carers to manage brain tumor related personality and behavior changes.
本范围综述的目的是描述旨在管理脑肿瘤患者人格和行为变化的心理社会干预措施的干预特征和效果。第二个目的是探讨这些干预措施是否对照顾者的结局产生影响。所考虑的人格和行为变化包括攻击性、冷漠、偏执、脱抑制和情绪不稳定。
本综述按照乔安娜·布里格斯研究所的范围综述方法以及系统评价和元分析的首选报告项目（PRISMA）范围综述扩展版进行。在心理学文摘数据库（PsycINFO）、护理学与健康领域数据库（CINAHL）、医学在线数据库（Ovid平台的Medline）和Scopus数据库中进行检索。我们综合了1996年至2022年发表的评估管理成人脑肿瘤相关人格和行为变化干预措施的研究。基于乔安娜·布里格斯研究所的模板使用了数据提取工具。结果呈现于汇总表中，并进行了叙述性综合分析。
共筛选了3594条记录。标题和摘要筛选后有29项可能符合条件的研究。全文筛选排除了24篇文章，5项干预措施符合纳入标准。这些干预措施在持续时间、实施方式、环境和参与情况（如患者个体或患者及其照顾者）方面各不相同。这些干预措施报告称，原发性脑肿瘤患者的目标人格和行为变化症状有所改善。四项研究纳入了人格和行为变化症状的测量，两项研究纳入了照顾者结局的测量，并报告了照顾者知识的改善和照顾者痛苦的减轻。所有研究的样本量均少于100名参与者。研究的随访数据有限，且使用了不同的工具来评估人格和行为变化的存在及性质。
缺乏心理社会干预措施来支持患者及其照顾者管理脑肿瘤相关的人格和行为变化。
