Department of Psychology, University of San Francisco, San Francisco, CA, USA.
Department of Social Work, National Taiwan University, Taipei, Taiwan; School of Nursing, University of California Los Angeles, Los Angeles, CA, USA.
Appl Nurs Res. 2023 Oct;73:151729. doi: 10.1016/j.apnr.2023.151729. Epub 2023 Aug 24.
Health disparities affecting persons living with HIV (PLWH) as well as those affecting individuals who use substances have been documented in China. However, health status and outcomes within the intersectional population of those who both live with HIV and use substances is not well understood. One hundred and sixty-nine PLWH receiving care in China completed surveys assessing HIV-clinical factors, substance use, and HIV-related physical health symptoms. We tested associations between substance use and health symptoms using multivariate logistic and ordinal regressions. Using one substance over the past week was associated with greater maximal severity of physical symptoms (p < .01); using two or more substances in the past week was associated with both increased total physical symptom severity (p < .05) and a dosage response in increased maximal severity (p < .01). Findings highlight the need for providers to address substance use for comprehensive care of PLWH to improve overall wellbeing.
在中国，有文献记录了影响艾滋病毒感染者（PLWH）以及影响物质使用者的健康差距。然而，对于同时患有艾滋病毒和使用物质的交叉人群的健康状况和结果，人们了解得还不够。在中国接受治疗的 169 名 PLWH 完成了评估 HIV 临床因素、物质使用和与 HIV 相关的身体健康症状的调查。我们使用多元逻辑回归和有序回归来测试物质使用与健康症状之间的关联。过去一周使用一种物质与身体症状的最大严重程度增加有关（p <.01）；过去一周使用两种或更多物质与身体总症状严重程度增加（p <.05）和最大严重程度的剂量反应增加（p <.01）有关。研究结果强调了提供者需要解决物质使用问题，以提供全面的 PLWH 护理，提高整体幸福感。
