Division of Infection Control, Dokkyo Medical University Saitama Medical Center, Japan.
Department of Infection Control and Prevention, The University of Tokyo Hospital, Japan.
Intern Med. 2024 Jun 15;63(12):1819-1822. doi: 10.2169/internalmedicine.1894-23. Epub 2023 Sep 15.
Although the frequency of community-acquired infections caused by Klebsiella pneumoniae subsp. ozaenae (K. ozaenae) is low, they are often detected in sputum specimens. In addition, lung abscesses, necrotizing pneumonia, and urinary tract infections caused by K. ozaenae have also been reported. We herein report the first detection of K. ozaenae as an etiological agent of bacterial meningitis in Japan. Cases of K. ozaenae meningitis complicated by diabetes mellitus and sinusitis have been reported elsewhere. When Klebsiella pneumoniae is detected in such cases, it is important to use other detection methods in addition to mass spectrometry for correct identification.
虽然洋葱伯克霍尔德菌（K. ozaenae）引起的社区获得性感染频率较低，但它们经常在痰标本中检测到。此外，还报道了由洋葱伯克霍尔德菌引起的肺脓肿、坏死性肺炎和尿路感染。我们在此报告了在日本首次发现洋葱伯克霍尔德菌作为细菌性脑膜炎的病原体。在其他地方也有报道称，糖尿病和鼻窦炎合并洋葱伯克霍尔德菌脑膜炎的病例。当在这些病例中检测到肺炎克雷伯菌时，除了使用质谱法外，还需要使用其他检测方法进行正确鉴定。
