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颌骨棕色瘤作为甲状旁腺功能亢进的罕见表现:两例报告及文献综述

Brown tumor of the jaw as a rare manifestation of hyperparathyroidism: Two case reports and literature review.

作者信息

Hakkou F, Benjelloun L, Hallab L, Chbicheb S

机构信息

Faculty of Dentistry-Rabat, Mohammed V University, Rabat, Morocco.

Faculty of Dentistry-Rabat, Mohammed V University, Rabat, Morocco.

出版信息

Int J Surg Case Rep. 2023 Oct;111:108823. doi: 10.1016/j.ijscr.2023.108823. Epub 2023 Sep 17.

Abstract

INTRODUCTION AND IMPORTANCE

Brown tumor is a giant cell focal lesion of bone associated with hyperparathyroidism, even primary or secondary. Differential diagnosis of these lesions from others giant cell lesions of the jaw bone is mandatory for the correct treatment of the patient.

CASE PRESENTATION

We present here two cases of brown tumor affecting the jaws by describing their clinical aspects and radiographic features, diagnostic criteria and treatment of this disease.

CLINICAL DISCUSSION

Brown tumor is one of the lesions that develop in patients with hyperparathyroidism or renal failure. Skeletal bones including maxillo-facial ones can be the site of this lesion, also radiographic and histopathological exams of the jaw lesion are not sufficient to determine the diagnosis, which requires laboratory tests and radiographic examination.

CONCLUSION

Dental surgeon should be aware of oral manifestations associated with systemic diseases, hence the importance of careful physical examination and thorough investigation for the diagnosis and treatment success. This article aims to illustrate the management strategy to aid clinicians in suspected cases of brown tumor.

摘要

引言与重要性

棕色瘤是一种与甲状旁腺功能亢进相关的骨巨细胞局灶性病变,包括原发性或继发性甲状旁腺功能亢进。为正确治疗患者,必须将这些病变与颌骨的其他巨细胞病变进行鉴别诊断。

病例介绍

我们在此介绍两例累及颌骨的棕色瘤病例,描述其临床症状、影像学特征、诊断标准及本病的治疗方法。

临床讨论

棕色瘤是甲状旁腺功能亢进或肾衰竭患者发生的病变之一。包括颌面骨在内的骨骼都可能是该病变的发生部位,而且颌骨病变的影像学和组织病理学检查不足以确定诊断,还需要实验室检查和影像学检查。

结论

牙科医生应了解与全身性疾病相关的口腔表现,因此仔细的体格检查和全面的检查对于诊断和治疗成功至关重要。本文旨在阐述管理策略,以帮助临床医生处理疑似棕色瘤病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fb/10518683/c2387c0d7dd9/gr1.jpg

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