Children's Mercy Kansas City, Kansas City, MO, USA.
University of Missouri-Kansas City, Kansas City, MO, USA.
BMC Pediatr. 2023 Sep 19;23(1):471. doi: 10.1186/s12887-023-04259-9.
Childhood obesity rates have continued to increase with the COVID-19 pandemic. However, data are limited on the impact of increasing obesity on associated comorbidities.
We evaluated the progression of overweight- or obesity-associated comorbidities by investigating change in laboratory results pre-COVID-19 pandemic and post-COVID-19 pandemic onset in youth with overweight or obesity. We defined progression of comorbidities based on increase in category rather than absolute change in value.
HbA1c progression was seen in 19%, and LDL cholesterol progression was seen in 26%, as defined by categories. HbA1c progression and LDL cholesterol progression were significantly correlated. HbA1c and LDL cholesterol progression were significantly associated with older age and Hispanics, respectively.
The results indicate youths with overweight or obesity have experienced progression of comorbidities during the COVID-19 pandemic. This study emphasizes the importance of early detection of comorbidities among a high-risk pediatric population.
随着 COVID-19 大流行的持续，儿童肥胖率持续上升。然而，关于肥胖程度增加对相关合并症的影响的数据有限。
我们通过调查超重或肥胖青少年在 COVID-19 大流行前和 COVID-19 大流行开始后的实验室结果变化，评估超重或肥胖相关合并症的进展情况。我们根据类别而不是绝对值的变化来定义合并症的进展。
以类别定义，19%的患者出现 HbA1c 进展，26%的患者出现 LDL 胆固醇进展。HbA1c 进展和 LDL 胆固醇进展呈显著相关。HbA1c 和 LDL 胆固醇的进展分别与年龄较大和西班牙裔显著相关。
研究结果表明，超重或肥胖的青少年在 COVID-19 大流行期间经历了合并症的进展。本研究强调了在高危儿科人群中早期发现合并症的重要性。
