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急性疼痛性霍纳综合征作为颈动脉夹层的首发症状

Acute Painful Horner Syndrome as the First Presenting Sign of Carotid Artery Dissection.

作者信息

Walburg Zachary G

机构信息

US Department of Veterans Affairs North Florida/South Georgia Healthcare System, Jacksonville, Florida.

出版信息

Fed Pract. 2023 May;40(5):160-166. doi: 10.12788/fp.0366. Epub 2023 Apr 20.

Abstract

BACKGROUND

Horner syndrome is a rare neurologic disorder that can arise from severe neurologic and systemic conditions, which may require immediate diagnosis with radiologic imaging and treatment with antiplatelet and anticoagulant therapy. Horner syndrome is often asymptomatic but can have distinct, easily identified characteristics seen with an ophthalmic examination.

CASE PRESENTATION

A 61-year-old woman presented with periorbital pain localized around and behind the right eye that she rated as 7 on a 10-point scale with onset 3 days prior. She reported light sensitivity, syncope, dizziness, and a recent history of transient ischemic attacks of unknown etiology. The patient had acute, slight ptosis with pathologic miosis and pain in the ipsilateral eye with no reports of exposure to miotic pharmaceutical agents and no history of trauma to the globe or orbit eliminated other differentials, leading to a diagnosis of right-sided Horner syndrome. She was referred for emergency department evaluation where radiography was indicative of an internal carotid artery dissection.

CONCLUSIONS

Due to possible life-threatening complications that can arise in patients with Horner syndrome, clinicians must have a thorough understanding of the condition, appropriate treatment, and management modalities. Determining the underlying etiology of Horner syndrome can help prevent a decrease in a patient's vision or quality of life and in some cases prevent death. Magnetic resonance imaging and computed tomography should be used to rule out carotid artery dissection and other severe conditions.

摘要

背景

霍纳综合征是一种罕见的神经系统疾病,可由严重的神经和全身疾病引起,可能需要通过放射影像学进行即时诊断,并采用抗血小板和抗凝治疗。霍纳综合征通常无症状,但在眼科检查中可出现明显且易于识别的特征。

病例介绍

一名61岁女性因右眼周围及眼后眶周疼痛就诊,她将疼痛程度评为10分制中的7分,疼痛于3天前开始。她报告有畏光、晕厥、头晕症状,且近期有病因不明的短暂性脑缺血发作史。患者出现急性、轻度上睑下垂,伴有病理性瞳孔缩小,同侧眼疼痛,无接触缩瞳药物史,无眼球或眼眶外伤史,排除了其他鉴别诊断,最终诊断为右侧霍纳综合征。她被转诊至急诊科评估,影像学检查显示为颈内动脉夹层。

结论

由于霍纳综合征患者可能出现危及生命的并发症,临床医生必须全面了解该疾病、适当的治疗方法和管理模式。确定霍纳综合征的潜在病因有助于预防患者视力下降或生活质量下降,在某些情况下还可预防死亡。应使用磁共振成像和计算机断层扫描来排除颈动脉夹层和其他严重疾病。

相似文献

4
Beware of "old" Horner syndrome.
Optom Vis Sci. 2012 Oct;89(10):e12-5. doi: 10.1097/OPX.0b013e318269cd69.
7
Ophthalmologic manifestations of internal carotid artery dissection.颈内动脉夹层的眼科表现。
Am J Ophthalmol. 1998 Oct;126(4):565-77. doi: 10.1016/s0002-9394(98)00136-6.

本文引用的文献

1
Horner syndrome: clinical perspectives.霍纳综合征:临床视角
Eye Brain. 2015 Apr 10;7:35-46. doi: 10.2147/EB.S63633. eCollection 2015.
6
Spontaneous dissection of the carotid and vertebral arteries.颈动脉和椎动脉自发性夹层
N Engl J Med. 2001 Mar 22;344(12):898-906. doi: 10.1056/NEJM200103223441206.

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