Gordon E, Kraiuhin C, Meares R, Howson A
J Psychiatr Res. 1986;20(3):237-48. doi: 10.1016/0022-3956(86)90006-3.
Event related potentials to frequently and infrequently occurring tones were recorded from 15 patients with somatization disorder, 10 patients with anxiety disorders and 15 normals. P3 component responses were of normal latency and amplitude in the somatizers, which suggests they had no apparent difficulty with certain aspects of processing novel, task-relevant stimuli. However, their N1 component responses to the frequent tones, which subjects had been instructed to ignore, were enhanced relative to each of the other groups. Moreover, there was no difference in N1 amplitude to the two types of tones among the somatizers, whereas each of the other groups had significantly larger N1 amplitudes to the infrequent tones. These preliminary results may suggest that somatization disorder is associated with an impaired ability to filter out and not respond to relatively meaningless afferent stimuli.
记录了15名躯体化障碍患者、10名焦虑症患者和15名正常人对频繁和不频繁出现音调的事件相关电位。躯体化障碍患者的P3成分反应潜伏期和波幅正常，这表明他们在处理新的、与任务相关的刺激的某些方面没有明显困难。然而，相对于其他两组，他们对频繁音调（受试者已被指示忽略）的N1成分反应增强。此外，躯体化障碍患者对两种类型音调的N1波幅没有差异，而其他每组对不频繁音调的N1波幅明显更大。这些初步结果可能表明，躯体化障碍与过滤掉相对无意义的传入刺激并对其不产生反应的能力受损有关。
