Department of Anesthesiology, Binzhou Medical University Hospital, Binzhou, China.
J Int Med Res. 2023 Sep;51(9):3000605231198385. doi: 10.1177/03000605231198385.
Essential thrombocythemia (ET) is a type of myeloproliferative neoplasm characterized by an abnormal increase in platelets. We report a female patient with a severe femoral fracture and ET who underwent the femoral intramedullary fracture fixation procedure. Her past medical history included hypertension and ET. On the second day of hospitalization, her platelet count was 922 × 10/L. In our case, general anesthesia combined with a femoral nerve block and a lateral femoral cutaneous nerve block were used when the platelet count was within normal range. After surgery, the platelet count increased to 979 × 10/L despite using anticoagulant drugs and hydroxyurea. The postoperative recovery went well after the follow-up of this patient. In this case report, we provide our experience of anesthesia management and review the progress of relevant literature to provide some reference.
原发性骨髓纤维化（ET）是一种以血小板异常增多为特征的骨髓增殖性肿瘤。我们报告了一例女性患者，因严重股骨骨折和 ET 接受了股骨髓内骨折固定术。她的既往病史包括高血压和 ET。住院第二天，她的血小板计数为 922×10/L。在我们的病例中，当血小板计数在正常范围内时，采用全身麻醉联合股神经阻滞和股外侧皮神经阻滞。尽管使用了抗凝药物和羟基脲，但术后血小板计数仍增加至 979×10/L。对该患者进行随访后，术后恢复良好。在本病例报告中，我们提供了我们的麻醉管理经验，并回顾了相关文献的进展，为其提供了一些参考。
