Department of Optometry (Z.W., L.F.), Shenyang Eye Institute, The 4th People's Hospital of Shenyang, China Medical University, Shenyang, Liaoning, China; Department of Ophthalmology (J.C.), Shengjing Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China; Department of Ophthalmology (J.K., T.N.), Shenyang Eye Institute, The 4th People's Hospital of Shenyang, China Medical University, Liaoning, China; and Department of Ophthalmology (L.G.), Shenyang Sinqi Eye Hospital, Shenyang, Liaoning, China.
Eye Contact Lens. 2023 Dec 1;49(12):512-520. doi: 10.1097/ICL.0000000000001025. Epub 2023 Sep 20.
To investigate the changes in choroidal thickness and axial length after orthokeratology in adolescents with low-to-moderate myopia and to explore the relationship between choroidal thickness and axial length variation.
Thirty eyes with low-to-moderate myopia were retrospectively studied, and optometric data were collected before and after 6 months of continuous orthokeratology. Axial length and choroidal and foveal thicknesses were measured using optical biometry and enhanced depth imaging-spectral domain optical coherence tomography, respectively.
Axial length in the low myopia group increased ( P <0.001) after 6 months of orthokeratology, and the variation was greater than that in the moderate myopia group ( P <0.05). The subfoveal choroidal thickness in low and moderate myopia groups increased ( P <0.01), and the variation was greater in the moderate myopia group ( P <0.05). Choroidal thickness in all seven measured spots increased, with the variation of subfovea, nasal 1 mm to fovea, and temporal 1 mm to fovea being statistically significant ( P <0.001, P <0.05, and P <0.05). The change in axial length was negatively associated with subfoveal and average choroidal thicknesses ( P <0.01).
Adolescents with moderate myopia presented better axial length control after 6 months of orthokeratology. The choroidal thickness of low and moderate myopic eyes increased, and the variation was more significant in moderate myopic eyes. The axial length control effects can be associated with an increase in the subfoveal and average choroidal thickness.
研究青少年中低度近视患者角膜塑形术后脉络膜厚度和眼轴长度的变化,并探讨脉络膜厚度变化与眼轴长度变化的关系。
回顾性研究 30 只低中度近视眼,连续角膜塑形 6 个月后收集其验光数据。采用光学生物测量仪和增强深度成像-谱域光相干断层扫描分别测量眼轴长度和脉络膜及中心凹厚度。
6 个月角膜塑形后,低中度近视组眼轴长度增加( P <0.001),且中度近视组变化大于低度近视组( P <0.05)。低、中度近视组中心凹下脉络膜厚度增加( P <0.01),且中度近视组变化大于低度近视组( P <0.05)。所有 7 个测量点的脉络膜厚度均增加,其中中心凹下、鼻侧 1mm 至中心凹、颞侧 1mm 至中心凹的变化具有统计学意义( P <0.001、 P <0.05 和 P <0.05)。眼轴长度的变化与中心凹下和平均脉络膜厚度呈负相关( P <0.01)。
青少年中低度近视患者角膜塑形 6 个月后眼轴长度控制更好。低、中度近视眼的脉络膜厚度增加,中度近视眼的变化更显著。轴向长度控制效果可能与中心凹下和平均脉络膜厚度的增加有关。