Instituto Dante Pazzanese de Cardiologia - São Paulo (SP), Brazil.
Rev Assoc Med Bras (1992). 2023 Sep 18;69(9):e20230607. doi: 10.1590/1806-9282.20230607. eCollection 2023.
The aim of this study was to evaluate the correlation between P-wave indexes, echocardiographic parameters, and CHA2DS2-VASc score in patients without atrial fibrillation and valvular disease.
This retrospective cross-sectional study included patients of a tertiary hospital with no history of atrial fibrillation, atrial flutter, or valve disease and collected data from June 2021 to May 2022. The exclusion criteria were as follows: unavailable medical records, pacemaker carriers, absence of echocardiogram report, or uninterpretable ECG. Clinical, electrocardiographic [i.e., P-wave duration, amplitude, dispersion, variability, maximum, minimum, and P-wave voltage in lead I, Morris index, PR interval, P/PR ratio, and P-wave peak time], and echocardiographic data [i.e., left atrium and left ventricle size, left ventricle ejection fraction, left ventricle mass, and left ventricle indexed mass] from 272 patients were analyzed.
PR interval (RHO=0.13, p=0.032), left atrium (RHO=0.301, p<0.001) and left ventricle diameter (RHO=0.197, p=0.001), left ventricle mass (RHO=0.261, p<0.001), and left ventricle indexed mass (RHO=0.340, p<0.001) were positively associated with CHA2DS2-VASc score, whereas P-wave amplitude (RHO=-0.141, p=0.02), P-wave voltage in lead I (RHO=-0.191, p=0.002), and left ventricle ejection fraction (RHO=-0.344, p<0.001) were negatively associated with the same score. The presence of the Morris index was associated with high CHA2DS2-VASc (p=0.022).
Prolonged PR interval, Morris index, increased left atrium diameter, left ventricle diameter, left ventricle mass, and left ventricle indexed mass values as well as lower P-wave amplitude, P-wave voltage in lead I, and left ventricle ejection fraction values were correlated with higher CHA2DS2-VASc scores.
本研究旨在评估无房颤和瓣膜病患者的 P 波指标、超声心动图参数和 CHA2DS2-VASc 评分之间的相关性。
这是一项回顾性的横断面研究，纳入了 2021 年 6 月至 2022 年 5 月期间来自一家三级医院的无房颤、房扑或瓣膜病病史的患者，并收集了患者的临床、心电图[即 P 波时限、幅度、离散度、变异性、最大、最小和 I 导联 P 波电压、Morris 指数、PR 间期、P/PR 比值和 P 波峰时间]和超声心动图[即左心房和左心室大小、左心室射血分数、左心室质量和左心室指数质量]数据。
PR 间期（RHO=0.13，p=0.032）、左心房（RHO=0.301，p<0.001）和左心室直径（RHO=0.197，p=0.001）、左心室质量（RHO=0.261，p<0.001）和左心室指数质量（RHO=0.340，p<0.001）与 CHA2DS2-VASc 评分呈正相关，而 P 波幅度（RHO=-0.141，p=0.02）、I 导联 P 波电压（RHO=-0.191，p=0.002）和左心室射血分数（RHO=-0.344，p<0.001）与该评分呈负相关。Morris 指数的存在与 CHA2DS2-VASc 评分高相关（p=0.022）。
PR 间期延长、Morris 指数、左心房直径、左心室直径、左心室质量和左心室指数质量增加以及 P 波幅度、I 导联 P 波电压和左心室射血分数降低与 CHA2DS2-VASc 评分升高相关。
