Department of Restorative, Preventive and Pediatric Dentistry, School of Dental Medicine, University of Bern, Freiburgstrasse 7, Bern 3010, Switzerland.
Department of Restorative, Preventive and Pediatric Dentistry, School of Dental Medicine, University of Bern, Freiburgstrasse 7, Bern 3010, Switzerland.
J Dent. 2023 Nov;138:104713. doi: 10.1016/j.jdent.2023.104713. Epub 2023 Sep 18.
The aim of this randomised, controlled, split-mouth trial was to assess the masking results in initial caries lesions (ICL) that were either resin infiltrated or fluoridated during treatment with fixed orthodontic appliances.
Adolescent patients (age range:12-18years) with fixed orthodontic appliances who had developed ICL [ICDAS 1 or 2 (International Caries Detection and Assessment System)] during orthodontic treatment were consecutively recruited and randomly assigned to either resin infiltration with up to 3 etching procedures (Group:Inf) or to 3-monthly application of a fluoride varnish (Group:FV). Both interventions were performed according to the manufacturer's recommendations. Primary and secondary outcomes (ΔE, ICDAS, DIAGNOdent) included the evaluation of the appearance of the ICL before (T), 1 week after (T) treatment and at the last appointment before debonding (T).
Fifteen patients (8females, 7males) with 57ICL were included. Mean (SD) observation time at the last appointment before debonding was 0.5 (0.3) years. At T FV and Inf did not differ significantly in ΔE (median ΔE(25th/75th percentiles):11.6 (8.7/20.3): ΔE:15.1 (11.4/19.5); p = 0.135), ICDAS (p = 0.920) and DD (p = 0.367). At T and T ΔE values (p<0.001, p<0.001), ICDAS scores (p<0.001, p<0.001) and DIAGNOdent values (p = <0.001, p = <0.001) for Inf were significantly reduced whereas ΔE values (p = 0.382, p = 0.072) and ICDAS scores (p = 0.268, p<0.001) for FV remained unchanged.
Resin infiltration effectively masked ICL during treatment with fixed orthodontic appliances both immediately after application and at the last appointment before debonding. Furthermore, the visual appearance of fluoridated lesions was not as satisfactory as that of the infiltrated ones at both T and T.
Resin infiltration effectively masked ICL during treatment with fixed orthodontic appliances both immediately after application and at the last appointment before debonding. Furthermore, the visual appearance of fluoridated lesions was not as satisfactory as that of the infiltrated ones immediately after first application as well as half a year after application.
German Clinical Trials Register (DRKS-ID: DRKS00011797).
本随机对照、分口研究旨在评估固定正畸矫治器治疗过程中，对早期龋损（ICL）进行树脂渗透或氟化处理后的掩蔽效果。
连续招募并随机分配接受固定正畸矫治的青少年患者（年龄范围：12-18 岁），他们在正畸治疗过程中出现 ICL[国际龋病检测与评估系统（ICDAS）1 或 2]。根据制造商的建议，对这些患者进行树脂渗透治疗（最多 3 次蚀刻程序，组：Inf）或每 3 个月应用一次氟化物漆（组：FV）。主要和次要结局（ΔE、ICDAS、DIAGNOdent）包括在治疗前（T）、治疗后 1 周（T）和最后一次拆除托槽前预约（T）时对 ICL 外观的评估。
共纳入 15 名患者（8 名女性，7 名男性），共 57 处 ICL。最后一次拆除托槽前预约时的平均（SD）观察时间为 0.5（0.3）年。在 T 时，FV 和 Inf 组在 ΔE（中位数ΔE（25 百分位/75 百分位）：11.6（8.7/20.3）：ΔE：15.1（11.4/19.5）；p=0.135）、ICDAS（p=0.920）和 DD（p=0.367）方面无显著差异。在 T 和 T 时，Inf 组的 ΔE 值（p<0.001，p<0.001）、ICDAS 评分（p<0.001，p<0.001）和 DIAGNOdent 值（p<0.001，p<0.001）均显著降低，而 FV 组的 ΔE 值（p=0.382，p=0.072）和 ICDAS 评分（p=0.268，p<0.001）则无变化。
树脂渗透在固定正畸矫治器治疗期间，无论是在治疗后立即还是在拆除托槽前的最后一次预约时，均能有效地掩盖 ICL。此外，与渗透后的病变相比，氟化物处理后的病变在 T 和 T 时的视觉效果都不太理想。
树脂渗透在固定正畸矫治器治疗期间，无论是在治疗后立即还是在拆除托槽前的最后一次预约时，均能有效地掩盖 ICL。此外，与渗透后的病变相比，氟化物处理后的病变在治疗后立即以及半年后的视觉效果都不太理想。
德国临床试验注册处（DRKS-ID：DRKS00011797）。
