Department of Psychiatry, Texas Tech University Health Science Center at Odessa/Permian Basin Odessa, TX, United States.
School of Medicine, Texas Tech University Health Science Center at Lubbock, TX, United States.
Psychiatry Res. 2022 Nov;317:114913. doi: 10.1016/j.psychres.2022.114913. Epub 2022 Oct 17.
Mental health disorders (MHD) and substance use disorders (SUD) lead to outstanding socioeconomic costs and increased hospital visits. However, very few studies have quantified this trend over time and across specific conditions. Our study aims to investigate and compare the prevalence of MHDs and SUDs in hospitalizations between 2007 and 2017.
We used hospital records for 2007 and 2017 from the National Inpatient Sample (NIS) datasets to identify young adults (18-44 years) hospitalized with MHD and SUD. The prevalence of MHD in hospitalized patients in 2017 vs. 2007 was measured and compared. We generated a multivariable logistic regression analysis controlled for confounders, including age, sex, race, and payer status. We evaluated these outcomes using Odds Ratio (OR) and 95% Confidence Interval (CI).
A total 10,353,890 patients were included in 2007, and 8,569,789 patients were included in 2017. The prevalence of drug abuse among hospitalized patients was 8.4% in 2017 vs. 6.2% in 2007. Prevalence increased in both genders (15.7% vs. 13.0% among male, 5.7% vs. 3.9% among females) in 2017 vs. 2007. All psychiatric disorders showed a higher prevalence in 2017 compared to 2007. When stratified by race, the prevalence of substance use disorder increased among all races except Black race between 2017 vs. 2007. On multivariable analysis, widespread drug abuse was significantly associated with hospital admissions in 2017 vs. 2007 (OR: 1.27, 95% CI: 1.20-1.34, p<0.001). These associations held across many substance abuse cases and mental health disorders except cocaine abuse (OR: 0.84, 95%CI: 0.76-0.93, p<0.001).
There was a significant rise in substance use disorder and psychiatric disorder a decade later, from 2007, in hospitalized patients in the age group 18-44 years. The most increase was observed in amphetamine use disorder and anxiety disorder. Suicide and intentional self-inflicted injury increased in all races, with a maximum increase observed in Native Americans. Further studies evaluating the factors responsible for this upward trend would be beneficial.
精神健康障碍（MHD）和物质使用障碍（SUD）会导致巨大的社会经济成本，并增加医院就诊次数。然而，很少有研究能够随着时间的推移和特定条件的变化来量化这种趋势。我们的研究旨在调查和比较 2007 年至 2017 年期间，医院住院患者中 MHD 和 SUD 的患病率。
我们使用了国家住院患者样本（NIS）数据集 2007 年和 2017 年的住院记录，以确定患有 MHD 和 SUD 的 18-44 岁的年轻成年人。测量并比较了 2017 年与 2007 年住院患者中 MHD 的患病率。我们生成了多变量逻辑回归分析，控制了混杂因素，包括年龄、性别、种族和支付者身份。我们使用优势比（OR）和 95%置信区间（CI）评估了这些结果。
2007 年共纳入 1035.389 例患者，2017 年共纳入 856.9789 例患者。2017 年，住院患者中药物滥用的患病率为 8.4%，而 2007 年为 6.2%。2017 年，男性（15.7%比 13.0%）和女性（5.7%比 3.9%）的患病率均有所增加。2017 年与 2007 年相比，所有精神疾病的患病率均有所升高。按种族分层，除黑人种族外，2017 年与 2007 年相比，所有种族的物质使用障碍患病率均有所增加。多变量分析显示，与 2007 年相比，2017 年广泛的药物滥用与住院治疗显著相关（OR：1.27，95%CI：1.20-1.34，p<0.001）。除可卡因滥用（OR：0.84，95%CI：0.76-0.93，p<0.001）外，这些关联在许多物质滥用病例和精神健康障碍中均成立。
从 2007 年到 18-44 岁的住院患者中，物质使用障碍和精神健康障碍在十年后显著增加。安非他命使用障碍和焦虑症的增幅最大。所有种族的自杀和故意自我伤害都有所增加，其中美洲原住民的增幅最大。进一步评估导致这种上升趋势的因素的研究将是有益的。
