Becker M
Lab Anim Sci. 1986 Aug;36(4):417-9.
This contribution describes a modern technique of producing general anesthesia in the Göttingen minipig. The method of anesthesia selected is dependent on the duration and type of surgery. The drugs used to produce anesthesia should not interfere with the experimental aims, therefore only drugs with well known actions and a standardized anesthesiological procedure should be used. Climazolam, Ketamine and atropine are preferred for induction of anesthesia. After endotracheal intubation, inhalation anesthetic mixed with oxygen and nitrous oxide is used to maintain general anesthesia. Controlled ventilation is necessary to prevent the animals from developing respiratory acidosis. Postoperative analgesia is provided by orally administering acetylsalicylate or morphine-sulfate pentahydrate at 12 hour intervals.
本论文介绍了一种在哥廷根小型猪中实施全身麻醉的现代技术。所选用的麻醉方法取决于手术的时长和类型。用于产生麻醉效果的药物不应干扰实验目的，因此应仅使用作用明确且麻醉程序标准化的药物。麻醉诱导首选氯咪唑仑、氯胺酮和阿托品。气管插管后，使用与氧气和一氧化二氮混合的吸入性麻醉剂维持全身麻醉。必须进行控制通气以防止动物发生呼吸性酸中毒。术后镇痛通过每隔12小时口服乙酰水杨酸或五水合硫酸吗啡来实现。
