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腰椎管狭窄症患者神经根冗余的临床意义及危险因素

[Clinical significance and risk factors of redundant nerve root in patients with lumbar spinal stenosis].

作者信息

Wu Zhong-Xuan, Xiao Liang, Zhao Quan-Lai, Liu Chen, Sun Hong-Zhou, Geng Yin, Jiang Yu-Jian

机构信息

Spine Surgery Research Center of Wannan Medical College, Department of Spine Surgery, Yijishan Hospital, the First Affiliated Hospital of Wannan Medical College, Wuhu 241001, Anhui, China.

出版信息

Zhongguo Gu Shang. 2023 Sep 25;36(9):890-5. doi: 10.12200/j.issn.1003-0034.2023.09.018.

Abstract

OBJECTIVE

To investigate the clinical significance and screen the risk factors of redundant nerve roots(RNRs) in patients with lumbar spinal stenosis.

METHODS

The clinical data of 196 patients with lumbar spinal stenosis in the department of Spinal Surgery, Yijishan Hospital, Wannan Medical College from April 1, 2015 to November 30, 2020 were retrospectively analyzed. All patients were divided into RNRs positive group and RNRs negative group according to the presence of RNRs. The differences in general clinical data, imaging parameters, visual analogue scale(VAS), Oswestry disability index(ODI), and other indicators between the two groups were compared. The risk factors which are highly correlated with RNRs were screened by binary Logistic regression analysis.

RESULTS

There were 59 cases in the RNRs positive group, with an occurrence rate of 29.95% (59/137), and 137 cases in the RNRs negative group. The incidence rate of RNRs in 196 patients with lumbar spinal stenosis was 30.10% (59/196). VAS and ODI scores of patients in the two groups were statistically significant (<0.05), and clinical symptoms of patients in the RNRs positive group were more severe than those in the RNRs negative group. There were significant differences in age, number of stenosis segments, average area of lumbar dural sac, area of the narrowest segment and the narrowest segment(<0.05). Binary logistic regression analysis showed that the number of stenosis segments, the average median sagittal diameter of spinal canal, and the average area of dural sac in lumbar intervertebral space were correlated with the generation of RNRs (<0.05). The regression coefficient of the number of stenosis segments was -1.115, the regression coefficient of the median sagittal diameter of the spinal canal was -1.707, and the regression coefficient of the mean dural sac area of the lumbar intervertebral space was 7.556.

CONCLUSION

The clinical symptoms of patients with lumbar spinal stenosis accompanied by RNRs are more severe than those without them. The number of narrow segments, median sagittal diameter of the spinal canal, and the area of the lumbar intervertebral dural sac are the high-risk factors for RNRs, with the area of the lumbar intervertebral dural sac has the highest correlation.

摘要

目的

探讨腰椎管狭窄症患者中冗余神经根(RNRs)的临床意义并筛查其危险因素。

方法

回顾性分析皖南医学院弋矶山医院脊柱外科2015年4月1日至2020年11月30日收治的196例腰椎管狭窄症患者的临床资料。根据是否存在RNRs将所有患者分为RNRs阳性组和RNRs阴性组。比较两组患者一般临床资料、影像学参数、视觉模拟评分法(VAS)、Oswestry功能障碍指数(ODI)等指标的差异。采用二元Logistic回归分析筛选与RNRs高度相关的危险因素。

结果

RNRs阳性组59例,发生率为29.95%(59/197),RNRs阴性组138例。196例腰椎管狭窄症患者中RNRs发生率为30.10%(59/196)。两组患者VAS和ODI评分差异有统计学意义(<0.05),RNRs阳性组患者临床症状较RNRs阴性组更严重。年龄、狭窄节段数、腰椎硬膜囊平均面积、最窄节段面积及最窄节段差异有统计学意义(<0.05)。二元Logistic回归分析显示,狭窄节段数、椎管平均矢状径、腰椎间隙硬膜囊平均面积与RNRs的发生相关(<0.05)。狭窄节段数的回归系数为-1.115,椎管矢状径的回归系数为-1.707,腰椎间隙硬膜囊平均面积的回归系数为7.556。

结论

伴有RNRs的腰椎管狭窄症患者临床症状较无RNRs者更严重。狭窄节段数、椎管矢状径、腰椎间隙硬膜囊面积是RNRs的高危因素,其中腰椎间隙硬膜囊面积相关性最高。

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