Huang Wenpeng, Chao Fangfang, Peng Yushuo, Zhang Xiaoyue, Yang Qi, Song Lele, Li Liming, Kang Lei
Department of Nuclear Medicine, Peking University First Hospital Beijing 100034, PR China.
Department of Nuclear Medicine, The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan, PR China.
Am J Nucl Med Mol Imaging. 2023 Aug 15;13(4):164-170. eCollection 2023.
Follicular lymphoma (FL) is a subtype of non-Hodgkin lymphoma (NHL) that is typically characterized by a slow-growing course. Duodenal-type follicular lymphoma (D-FL) was recently reclassified as a distinct variant. This subtype exhibits unique clinical and biological characteristics, which set it apart from other forms of FL. We report a case of a 36-year-old male patient with multiple, small, gray polypoid lesions in the descending duodenum which were detected by esophagogastroduodenoscopy. The pathological diagnosis was low-grade D-FL. F-FDG PET/CT was performed for staging and revealed the pancreas and peripheral lymph nodes were involved by FL, with a clinical IV stage. The patient underwent a bone marrow smear cytology, which revealed no bone marrow abnormalities, and excluded bone marrow involvement. He was treated with six cycles of chemotherapy using the R-CHOP regimen and reached complete remission.
滤泡性淋巴瘤（FL）是非霍奇金淋巴瘤（NHL）的一种亚型，其典型特征为病程进展缓慢。十二指肠型滤泡性淋巴瘤（D-FL）最近被重新归类为一种独特的变体。该亚型具有独特的临床和生物学特征，使其有别于其他形式的FL。我们报告一例36岁男性患者，经食管胃十二指肠镜检查发现降部十二指肠有多个小的灰色息肉样病变。病理诊断为低级别D-FL。进行了F-FDG PET/CT分期检查，结果显示胰腺和外周淋巴结有FL累及，临床分期为IV期。该患者接受了骨髓涂片细胞学检查，结果显示无骨髓异常，排除了骨髓受累。他接受了六个周期的R-CHOP方案化疗，达到完全缓解。
