Han Jung-Yong, Cho Soo-Kyung, Sung Yoon-Kyoung
Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.
Hanyang University Institute for Rheumatology Research, Seoul, Korea.
J Rheum Dis. 2023 Oct 1;30(4):211-219. doi: 10.4078/jrd.2023.0037. Epub 2023 Sep 11.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by diverse organ system disabilities, predominantly affecting young females. The clinical manifestations of SLE encompass various organs, including the kidney, cardiovascular system, and central nervous system. Young females with SLE experience higher mortality rates than the general population, making it imperative to gain insights into the disease patterns and associated factors. The current review examines the epidemiological studies to analyze the prevalence, incidence, and mortality trends of SLE in Korea and compares them with the findings from other countries. We aim to identify potential similarities, differences, and factors contributing to the burden of SLE in different populations by exploring the comparative epidemiological aspects. The knowledge derived from this comparison would aid in advancing the overall management of SLE in Korea.
系统性红斑狼疮(SLE)是一种慢性自身免疫性疾病,其特征是多器官系统功能障碍,主要影响年轻女性。SLE的临床表现累及多个器官,包括肾脏、心血管系统和中枢神经系统。患有SLE的年轻女性死亡率高于普通人群,因此深入了解疾病模式和相关因素至关重要。本综述通过对流行病学研究进行分析,探讨韩国SLE的患病率、发病率和死亡率趋势,并与其他国家的研究结果进行比较。我们旨在通过探索比较流行病学方面,确定不同人群中SLE负担的潜在异同点及相关因素。通过这种比较获得的知识将有助于推动韩国SLE的整体管理。