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[真菌性足菌肿的实际治疗:酮康唑与保守手术联合应用的意义]

[Actual treatment of fungus mycetoma: interest in associating ketoconazole and conservative surgery].

作者信息

Andreu J M

出版信息

Med Trop (Mars). 1986 Jul-Sep;46(3):293-7.

PMID:3773686
Abstract

The author diagnosed and treated 66 cases of fungus mycetomae during his two years of assignment at the Nouakchott national hospital (Islamic Republic of Mauritania). Recent coming out of the youngest generation of an antifungus drug: ketoconazole, leads the author to change his therapeutic attitude towards such tumours. This article reports on promising results got by an original medico-surgical association. The interest of such a treatment is also underlined by the poor results of the classical treatment, solely surgical, when it tries to be conservative.

摘要

作者在毛里塔尼亚伊斯兰共和国努瓦克肖特国立医院工作的两年间,诊断并治疗了66例真菌性足菌肿病例。新一代抗真菌药物酮康唑的问世,促使作者改变了对这类肿瘤的治疗态度。本文报道了一种原创性药物与手术联合疗法所取得的喜人成果。经典的单纯手术保守治疗效果不佳,也凸显了这种联合治疗方法的优势。

相似文献

1
[Actual treatment of fungus mycetoma: interest in associating ketoconazole and conservative surgery].[真菌性足菌肿的实际治疗:酮康唑与保守手术联合应用的意义]
Med Trop (Mars). 1986 Jul-Sep;46(3):293-7.
2
[Mycetoma of the neck and the nape of the neck due to Madurella mycetomatis. Apropos of a case in Mauritania].[马杜拉分支菌引起的颈部和颈背部足菌肿。关于毛里塔尼亚的一例病例]
Bull Soc Pathol Exot. 1995;88(3):103-4.
3
[Value of ketoconazole in combination with the surgical treatment of fungal mycetoma].酮康唑联合手术治疗真菌性足菌肿的价值
Chirurgie. 1986;112(2):163-9.
4
[Mycetoma of the hand. Apropos of 10 cases].[手部足菌肿。附10例报告]
Ann Chir. 1989;43(10):814-23.
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[Surgical therapy in African mycetoma. Indications a propos of 160 cases].[非洲足菌肿的外科治疗。关于160例病例的适应症]
Med Trop (Mars). 1986 Jul-Sep;46(3):283-92.
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Treatment of eumycetoma and actinomycetoma.真菌性足菌肿和放线菌性足菌肿的治疗。
Curr Top Med Mycol. 1995;6:47-71.
7
[Mycetoma caused by Petriellidium boydii: treatment with ketoconazole].
Hautarzt. 1985 Aug;36(8):453-8.
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Madura foot of the chest wall; cure after radical excision.胸壁马杜拉足;根治性切除术后治愈。
Thorac Cardiovasc Surg. 1992 Aug;40(4):198-200. doi: 10.1055/s-2007-1020149.
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[Mycetoma].[足菌肿]
Klin Khir (1962). 1990(1):26-9.
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Pseudallescheria boydii infections treated with ketoconazole. Clinical evaluations of seven patients and in vitro susceptibility results.酮康唑治疗波氏假阿利什菌感染。7例患者的临床评估及体外药敏结果。
Chest. 1984 Aug;86(2):219-24. doi: 10.1378/chest.86.2.219.

引用本文的文献

1
Mycetoma (Madura Foot): A Case Report of Misdiagnosis and Recovery in a Young Patient.
Cureus. 2025 Oct 12;17(10):e94400. doi: 10.7759/cureus.94400. eCollection 2025 Oct.
2
In vitro susceptibilities of Madurella mycetomatis to itraconazole and amphotericin B assessed by a modified NCCLS method and a viability-based 2,3-Bis(2-methoxy-4-nitro-5- sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium hydroxide (XTT) assay.通过改良的美国国立临床实验室标准化委员会(NCCLS)方法和基于活性的2,3-双(2-甲氧基-4-硝基-5-磺基苯基)-5-[(苯胺基)羰基]-2H-氢氧化四唑(XTT)测定法评估马杜拉足分支菌对伊曲康唑和两性霉素B的体外敏感性。
Antimicrob Agents Chemother. 2004 Jul;48(7):2742-6. doi: 10.1128/AAC.48.7.2742-2746.2004.
3
Madura foot: a surgical cure.马杜拉足:一种手术疗法。
BMJ. 1991 Oct 19;303(6808):994. doi: 10.1136/bmj.303.6808.994-a.