Fox U, Ferro M, Camozzi L, Conti G, Montorsi W
Microsurgery. 1986;7(3):128-31. doi: 10.1002/micr.1920070306.
The repercussions on the venous wall of the creation of 20 artero-venous anastomoses (AVA) between the femoral artery and vein of the rat have been evaluated. The rats were killed 7, 15, 30, and 90 days after AVA, and AVAs were examined by optical microscopy and by scanning electronic microscopy. Deposits of whitish material that nearly completely occluded the venous lumen were seen, especially in the group studied longer than 90 days. These venous wall lesions, which resemble arteriosclerotic lesions, must be attributed to the new hemodynamic situation created by the AVA. The implications of such findings for the long-term validity of venous graft in vascular microsurgery and the long-term patency of the AVA in hemodialyzed children are discussed.
已评估在大鼠股动脉和静脉之间创建20个动静脉吻合术（AVA）对静脉壁的影响。在进行AVA后的7天、15天、30天和90天处死大鼠，并通过光学显微镜和扫描电子显微镜检查AVA。可见白色物质沉积，几乎完全阻塞了静脉管腔，尤其是在研究时间超过90天的组中。这些类似于动脉粥样硬化病变的静脉壁病变，必须归因于AVA所造成的新的血流动力学状况。讨论了这些发现对血管显微外科中静脉移植物长期有效性以及血液透析儿童中AVA长期通畅性的影响。
