[Effect of diazepam and phenobarbital on the acute toxicity of bicyclic organophosphorus esters].
作者信息
Smok W, Emilianowicz J
出版信息
Med Pr. 1986;37(3):158-61.
PMID:3773696
Abstract
Bicyclic phosphorus esters (BCP) originating from the combustion of fire-retardant polyurethane foam containing phosphorus are highly toxic compounds and potent antagonists of GABA-ergic receptors. The clinical symptoms of the poisoning are grand mal seizures. The results of experiments on rats demonstrated that diazepam and phenobarbital reduce acute toxicity of the isopropyl-BCP-derivative and remarkably smooth poisoning symptoms.
摘要
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