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社区居住的老年人虚弱指数的可靠性。

Reliability of the Frailty Index Among Community-Dwelling Older Adults.

机构信息

Institute of Social Medicine and Epidemiology, Medical University of Graz, Graz, Austria.

Geriatric Medicine, Dalhousie University and Nova Scotia Health, Halifax, Nova Scotia, Canada.

出版信息

J Gerontol A Biol Sci Med Sci. 2024 Feb 1;79(2). doi: 10.1093/gerona/glad227.

Abstract

BACKGROUND

Consistent and reproducible estimates of the underlying true level of frailty are essential for risk stratification and monitoring of health changes. The purpose of this study is to examine the reliability of the frailty index (FI).

METHODS

A total of 426 community-dwelling older adults from the FRequent health Assessment In Later life (FRAIL70+) study in Austria were interviewed biweekly up to 7 times. Two versions of the FI, one with 49 deficits (baseline), and another with 44 (follow-up) were created. Internal consistency was assessed using confirmatory factor analysis and coefficient omega. Test-retest reliability was assessed with Pearson correlation coefficients and the intraclass correlation coefficient. Measurement error was assessed with the standard error of measurement, limits of agreement, and smallest detectable change.

RESULTS

Participants (64.6% women) were on average 77.2 (±5.4) years old with mean FI49 at a baseline of 0.19 (±0.14). Internal consistency (coefficient omega) was 0.81. Correlations between biweekly FI44 assessments ranged between 0.86 and 0.94 and reliability (intraclass correlation coefficient) was 0.88. The standard error of measurement was 0.05, and the smallest detectable change and upper limits of agreement were 0.13; the latter is larger than previously reported minimal clinically meaningful changes.

CONCLUSIONS

Both internal consistency and reliability of the FI were good, that is, the FI differentiates well between community-dwelling older adults, which is an important requirement for risk stratification for both group-level oriented research and patient-level clinical purposes. Measurement error, however, was large, suggesting that individual health deteriorations or improvements, cannot be reliably detected for FI changes smaller than 0.13.

摘要

背景

为了进行风险分层和监测健康变化,一致且可重复的衰弱真实水平估计至关重要。本研究旨在检验衰弱指数(FI)的可靠性。

方法

奥地利 FRequent health Assessment In Later life(FRAIL70+)研究中共有 426 名社区居住的老年人接受了最多 7 次的双周访谈。创建了两种 FI 版本,一种有 49 个缺陷(基线),另一种有 44 个(随访)。使用验证性因子分析和系数ω评估内部一致性。使用 Pearson 相关系数和组内相关系数评估测试-重测可靠性。使用测量误差的标准误差、界限协议和最小可检测变化评估测量误差。

结果

参与者(64.6%为女性)平均年龄为 77.2(±5.4)岁,平均 FI49 在基线时为 0.19(±0.14)。内部一致性(系数ω)为 0.81。FI44 双周评估之间的相关性在 0.86 到 0.94 之间,可靠性(组内相关系数)为 0.88。测量误差的标准误差为 0.05,最小可检测变化和上限协议分别为 0.13;后者大于先前报告的最小临床有意义变化。

结论

FI 的内部一致性和可靠性都很好,即 FI 能很好地区分社区居住的老年人,这是进行群体水平研究和患者水平临床目的的风险分层的重要要求。然而,测量误差较大,表明 FI 变化小于 0.13 时,无法可靠地检测个体健康恶化或改善。

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