Food Science Graduate Program, Center of Agrarian Sciences, Universidade Estadual de Maringá (UEM), Colombo Avenue, 5790, 87020-900, Maringá, Parana, Brazil.
Centro Universitário São Camilo, Raul Pompéia Street, 144, 05025-011, São Paulo, Brazil.
Clin Nutr ESPEN. 2023 Oct;57:288-296. doi: 10.1016/j.clnesp.2023.06.007. Epub 2023 Jun 16.
BACKGROUND & AIMS: The present study evaluated the lipid profile of enteral nutrition formulas with added fish oil used in a public hospital, with an emphasis on the fatty acid (FA) composition.
FA composition was determined using gas chromatography coupled to a flame ionization detector (GC-FID). Nine enteral nutrition formulas were evaluated and the results obtained were compared with those reported on the formulas labels.
The sample with the highest percentage of added fish oil according to the label information had the lowest total amounts of eicosapentaenoic acid and docosahexaenoic acid (EPA + DHA) (p < 0.05). In the evaluation of the total amount of polyunsaturated fatty acids/saturated fatty acids (ΣPUFA/ΣSFA) ratio, five samples were not within the values recommended by Brazilan and international health regulatory agencies. Regarding the n-6/n-3 fatty acids ratio, five samples showed values higher than the recommended ratio. It was observed that EPA + DHA content was positively correlated with the cost of the diet. Importantly, we also found that there was a significant difference between the results of our analysis and the descriptions found on the labels for fatty acids n-6, n-3, EPA, DHA, SFA, PUFA and MUFA.
We conclude that the discrepancies for fatty acids between the values obtained in the analyses and the values reported on the labels highlight the need for more rigorous inspection when public hospitals purchase enteral nutrition formulas with added fish oil, since the administration of formulas with inadequate levels of FA in hospitalized patients can compromise clinical results during the hospitalization period.
本研究评估了一家公立医院使用的添加鱼油的肠内营养配方的脂质谱，重点是脂肪酸（FA）组成。
使用气相色谱法结合火焰离子化检测器（GC-FID）测定 FA 组成。评估了 9 种肠内营养配方，并将所得结果与配方标签上报告的结果进行了比较。
根据标签信息，添加鱼油百分比最高的样品的二十碳五烯酸和二十二碳六烯酸（EPA+DHA）总量最低（p<0.05）。在多不饱和脂肪酸/饱和脂肪酸（ΣPUFA/ΣSFA）比值的总评估中，有 5 种样品不在巴西和国际健康监管机构推荐的值范围内。关于 n-6/n-3 脂肪酸比值，有 5 种样品的值高于推荐值。观察到 EPA+DHA 含量与饮食成本呈正相关。重要的是，我们还发现分析结果与标签上的脂肪酸 n-6、n-3、EPA、DHA、SFA、PUFA 和 MUFA 描述之间存在显著差异。
我们得出结论，分析中获得的脂肪酸值与标签上报告的值之间的差异表明，公立医院在购买添加鱼油的肠内营养配方时需要更严格的检查，因为在住院患者中给予 FA 水平不足的配方可能会影响住院期间的临床结果。
