Jeffrey M, Wells G A
Neuropathol Appl Neurobiol. 1986 Jul-Aug;12(4):415-24. doi: 10.1111/j.1365-2990.1986.tb00152.x.
Multifocal, arterial, fibrocartilaginous embolism of the cervical spinal cord, medulla oblongata and cerebellum is described in a neonatal lamb. The emboli contained mucosubstances which, by the Alcian blue critical electrolyte concentration method, were identified as mainly keratan sulphate. This composition indicates the probable origin of emboli from the nucleus pulposus of intervertebral discs. Possible modes of entry of such material into the spinal cord vasculature are reviewed and a mechanism proposed to explain the localization of emboli in spinal cord, brain stem and cerebellar arteries in this case.
本文描述了一只新生羔羊发生的颈脊髓、延髓和小脑的多灶性、动脉性、纤维软骨栓塞。栓子含有黏液物质,通过阿尔辛蓝临界电解质浓度法鉴定,主要为硫酸角质素。这种成分表明栓子可能起源于椎间盘的髓核。本文回顾了此类物质进入脊髓血管系统的可能途径,并提出了一种机制来解释该病例中栓子在脊髓、脑干和小脑动脉中的定位。