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[儿童洋地黄中毒。用抗地高辛Fab抗体片段治疗。结合一例病例及治疗指征的讨论]

[Digitalis poisoning in children. Treatment with anti-digoxin Fab antibody fragments. Apropos of a case and a discussion of therapeutic indications].

作者信息

Jouk P S, Danel V, Bovier-Lapierre M, Frappat P, Barret L, Rossignol A M, Bost M

出版信息

Pediatrie. 1986 Apr-May;41(3):237-42.

PMID:3774436
Abstract

We report one case of Digoxin intoxication in a child treated with Fab Fragments of Digoxin-Specific antibodies (Fabad), although there was no evidence of early life threatening complications. The efficacy of this treatment, which prevents further complications as well as its safety, represent strong arguments to treat children at the early stage of the intoxication in order to avoid temporary cardiac pacing.

摘要

我们报告一例接受地高辛特异性抗体片段(Fabad)治疗的儿童地高辛中毒病例,尽管尚无早期危及生命并发症的证据。这种治疗方法可预防进一步并发症且具有安全性,这有力地支持了在中毒早期对儿童进行治疗,以避免临时心脏起搏。

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