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妊娠合并爱泼斯坦-巴尔病毒再激活相关的脑膜脑炎伴横贯性脊髓炎

Epstein-Barr virus reactivation-related meningoencephalitis with transverse myelitis in pregnancy.

作者信息

Nguyen Andrew Dang Khai, Siu Ronald, Kleinschmidt Grant, Sood Bimal Prakash, Shandiz Ehsan Esmaili

机构信息

Darling Downs Health Service, Queensland Health Toowoomba Hospital Toowoomba Queensland Australia.

University of Queensland Rural Clinical School Toowoomba Queensland Australia.

出版信息

Clin Case Rep. 2023 Sep 21;11(9):e7923. doi: 10.1002/ccr3.7923. eCollection 2023 Sep.

DOI:10.1002/ccr3.7923
PMID:37744622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10514378/
Abstract

KEY CLINICAL MESSAGE

Consider the differential of Epstein-Barr virus (EBV) reactivation in pregnant women who develop progressive meningoencephalitis and transverse myelitis. EBV nucleic acid amplification should be considered in immunosuppressed patients.

ABSTRACT

A 32-year-old G10P6M3K22 pregnant female presented to a regional hospital with progressive severe neurological and behavioral deficits. Magnetic resonance revealed cervical transverse myelitis. Lumbar puncture confirmed Epstein-Barr virus (EBV) DNA on a background of IgG-positive EBV serology. A diagnosis of EBV reactivation-related meningoencephalitis with transverse myelitis in pregnancy was concluded.

摘要

关键临床信息

对于出现进行性脑膜脑炎和横贯性脊髓炎的孕妇，应考虑爱泼斯坦-巴尔病毒（EBV）再激活的鉴别诊断。免疫抑制患者应考虑进行EBV核酸扩增检测。

摘要

一名32岁、孕10产6流3存2的孕妇因进行性严重神经和行为缺陷就诊于一家地区医院。磁共振成像显示颈髓横贯性脊髓炎。腰椎穿刺在IgG阳性的EBV血清学背景下证实了EBV DNA。最终诊断为妊娠合并EBV再激活相关的脑膜脑炎伴横贯性脊髓炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d882/10514378/75a5b22eabed/CCR3-11-e7923-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d882/10514378/8dc64076af15/CCR3-11-e7923-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d882/10514378/75a5b22eabed/CCR3-11-e7923-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d882/10514378/8dc64076af15/CCR3-11-e7923-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d882/10514378/75a5b22eabed/CCR3-11-e7923-g002.jpg

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