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新型冠状病毒2型感染的急性心脏表现:发现血栓形成

Acute Cardiac Manifestations of SARS-CoV-2 Infection: Spotting the Clot.

作者信息

Kerley Robert N, John Amal, Matiullah Sajjad, Rogan Mark

机构信息

Department of Medicine, University College Cork, Ireland.

University Hospital Waterford, Dunmore Road, Waterford, Ireland.

出版信息

Case Rep Cardiol. 2023 Sep 14;2023:6366959. doi: 10.1155/2023/6366959. eCollection 2023.

Abstract

A middle-aged gentleman presented with a one-week history of progressive dyspnoea on minimal exertion, persistent haemoptysis, and right calf swelling. His only past medical history of note was a recently positive SARS-CoV-2 nasopharyngeal swab performed as part of a workplace outbreak screening. A CT pulmonary angiogram (CTPA) showed bilateral pulmonary thrombi, extensive consolidation, and a left ventricular (LV) thrombus. A transthoracic echocardiogram (TTE) showed a dilated LV with severely impaired systolic function and LV thrombus. The patient was anticoagulated with warfarin, commenced on IV diuretics and COVID-19 protocol. Cardiac magnetic resonance (CMR) imaging showed a severely dilated nonischaemic cardiomyopathy with a heavy thrombus burden and a fibrosis pattern in keeping with myocarditis. We present a case of COVID-19-related myocardial dysfunction with high thrombotic burden and a discussion of its management.

摘要

一名中年男性患者,出现了为期一周的进行性呼吸困难症状,轻微活动即感不适,伴有持续咯血及右小腿肿胀。他唯一值得注意的既往病史是近期作为工作场所疫情筛查一部分进行的鼻咽拭子检测,结果显示SARS-CoV-2呈阳性。胸部CT血管造影(CTPA)显示双侧肺血栓、广泛实变以及左心室(LV)血栓。经胸超声心动图(TTE)显示左心室扩张,收缩功能严重受损且存在左心室血栓。患者接受了华法林抗凝治疗,开始静脉注射利尿剂并遵循新冠病毒治疗方案。心脏磁共振(CMR)成像显示严重扩张的非缺血性心肌病,伴有大量血栓负荷以及符合心肌炎的纤维化模式。我们报告了一例伴有高血栓负荷的新冠病毒相关心肌功能障碍病例,并对其治疗进行了讨论。

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