2019冠状病毒病相关性心肌炎：对病理生理学及管理的见解
Coronavirus Disease 2019 Myocarditis: Insights into Pathophysiology and Management.
作者信息
Abdelnabi Mahmoud, Eshak Nouran, Saleh Yehia, Almaghraby Abdallah
机构信息
Cardiology and Angiology Unit, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, Alexandria University Alexandria, Egypt.
Rheumatology Unit, Department of Internal Medicine, Faculty of Medicine, Alexandria University Alexandria, Egypt.
出版信息
Eur Cardiol. 2020 Jun 17;15:e51. doi: 10.15420/ecr.2020.16. eCollection 2020 Feb.
Abstract
The world is dealing with a global pandemic of severe acute respiratory coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19), which is the illness caused by SARS-CoV-2, is overwhelming healthcare systems around the world. Although the main clinical manifestations of COVID-19 are respiratory symptoms, several reports have noted myocarditis, cardiomyopathy, arrhythmias and cardiac arrests as COVID-19 complications. Here, the authors highlight the current understanding of the pathophysiology of myocarditis related to COVID-19 and its management.
摘要
全球正在应对由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引发的全球大流行。2019冠状病毒病（COVID-19）是由SARS-CoV-2引起的疾病，正在使世界各地的医疗系统不堪重负。尽管COVID-19的主要临床表现为呼吸道症状，但已有多篇报告指出，心肌炎、心肌病、心律失常和心脏骤停是COVID-19的并发症。在此，作者着重介绍了目前对与COVID-19相关的心肌炎病理生理学及其治疗的认识。
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本文引用的文献
1
Recognizing COVID-19-related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management.
Heart Rhythm. 2020 Sep;17(9):1463-1471. doi: 10.1016/j.hrthm.2020.05.001. Epub 2020 May 5.
2
First case of COVID-19 complicated with fulminant myocarditis: a case report and insights.
Infection. 2020 Oct;48(5):773-777. doi: 10.1007/s15010-020-01424-5. Epub 2020 Apr 10.
3
Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).
JAMA Cardiol. 2020 Jul 1;5(7):819-824. doi: 10.1001/jamacardio.2020.1096.
4
Coronavirus fulminant myocarditis treated with glucocorticoid and human immunoglobulin.
Eur Heart J. 2021 Jan 7;42(2):206. doi: 10.1093/eurheartj/ehaa190.
5
SARS-CoV-2: a potential novel etiology of fulminant myocarditis.
Herz. 2020 May;45(3):230-232. doi: 10.1007/s00059-020-04909-z.
6
COVID-19 and the cardiovascular system.
Nat Rev Cardiol. 2020 May;17(5):259-260. doi: 10.1038/s41569-020-0360-5.
7
Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China.
Intensive Care Med. 2020 May;46(5):846-848. doi: 10.1007/s00134-020-05991-x. Epub 2020 Mar 3.
8
Corticosteroids for viral myocarditis.
Cochrane Database Syst Rev. 2013 Oct 18;2013(10):CD004471. doi: 10.1002/14651858.CD004471.pub3.
9
Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases.
Eur Heart J. 2013 Sep;34(33):2636-48, 2648a-2648d. doi: 10.1093/eurheartj/eht210. Epub 2013 Jul 3.
10
A systematic review of intravenous gamma globulin for therapy of acute myocarditis.
BMC Cardiovasc Disord. 2005 Jun 2;5(1):12. doi: 10.1186/1471-2261-5-12.
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