Makoto Murahashi, Ntege Edward Hosea, Kazuhide Nishihara, Kentaro Ide, Jumpei Shirakawa, Nobuyuki Maruyama, Toshihiro Kawano, Yusuke Shimizu, Hiroyuki Nakamura
Department of Oral and Maxillofacial Surgery, Urasoe General Hospital, Urasoe, Okinawa 901-2132, Japan.
Department of Oral and Maxillofacial Functional Rehabilitation, Graduate School of Medicine, University of the Ryukyus, Nakagami, Nishihara, Okinawa 903-0215, Japan.
Mol Clin Oncol. 2023 Sep 1;19(4):83. doi: 10.3892/mco.2023.2679. eCollection 2023 Oct.
Metastatic colorectal carcinoma involving the maxilla is a rare phenomenon, and existing literature regarding the significance of perioperative oral function management (POM) in managing such cases is limited. In the present case report the clinical details of a 58-year-old male referred to the oral and maxillofacial department for POM. The patient had previously undergone segmental bowel resection due to stage IIIb colon cancer. A comprehensive approach encompassing a thorough medical history, meticulous physical examination, radiographic imaging and immunohistopathology was employed, and a definitive diagnosis of metastatic adenocarcinoma in the left maxillary gingiva originating from a colorectal carcinoma was reached. Additionally, concomitant metastases were detected in the lungs and liver. Despite the daunting prognosis associated with the metastases in the oral cavity, the patient's quality of life exhibited discernible improvements owing to the implementation of palliative care interventions. Notably, this interdisciplinary approach facilitated the patient's survival for over a year. The present case report strongly advocates for the prompt integration of POM in the surgical management of cancer patients with oral manifestations, which can optimize both the quality of life and overall survival.
上颌骨转移性结直肠癌是一种罕见现象,现有关于围手术期口腔功能管理(POM)在这类病例管理中意义的文献有限。在本病例报告中,介绍了一名58岁男性因POM转诊至口腔颌面科的临床细节。该患者此前因IIIb期结肠癌接受了节段性肠切除术。采用了综合方法,包括详细的病史、细致的体格检查、影像学检查和免疫组织病理学检查,最终确诊为起源于结直肠癌的左上颌牙龈转移性腺癌。此外,在肺部和肝脏检测到了伴随转移。尽管口腔转移预后不佳,但由于实施了姑息治疗干预措施,患者的生活质量有了明显改善。值得注意的是,这种多学科方法使患者存活了一年多。本病例报告强烈主张在有口腔表现的癌症患者的手术管理中迅速纳入POM,这可以优化生活质量和总生存期。