Mahadevan Aditya, Warnecke Brian, Chiao Elaine, Nafissi Nellie, Parajuli Kritisha, Rijal Nejina, Parajuli Ritesh
Department of Hematology and Oncology, University of California Irvine School of Medicine, Orange, USA.
Department of Hematology and Oncology, University of California Irvine Medical Center, Orange, USA.
Cureus. 2023 Sep 21;15(9):e45692. doi: 10.7759/cureus.45692. eCollection 2023 Sep.
A chemical burn resulting from luteinizing hormone-releasing hormone agonists (LHRHa) is a rare adverse effect that has not been well-documented in prior literature. In this case report, we report a partial-thickness burn that developed following a single subcutaneous injection of goserelin. To our knowledge, this is the first description of goserelin-induced chemical burn in the literature. The importance of early identification and treatment of LHRHa-associated cutaneous reactions must be highlighted to ensure optimal oncologic management and patient comfort.
促黄体生成素释放激素激动剂（LHRHa）导致的化学灼伤是一种罕见的不良反应，既往文献中对此记载不多。在本病例报告中，我们报告了一例单次皮下注射戈舍瑞林后发生的浅二度烧伤。据我们所知，这是文献中对戈舍瑞林诱导的化学灼伤的首次描述。必须强调早期识别和治疗LHRHa相关皮肤反应的重要性，以确保最佳的肿瘤管理和患者舒适度。
