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免疫功能正常的儿童孤立性结核性纵隔淋巴结肿大且无肺部受累:一例报告

Isolated Tuberculous Mediastinal Lymphadenopathy in an Immunocompetent Child Without Pulmonary Involvement: A Case Report.

作者信息

Yadav Sankalp

机构信息

Medicine, Shri Madan Lal Khurana Chest Clinic, New Delhi, IND.

出版信息

Cureus. 2023 Aug 23;15(8):e43987. doi: 10.7759/cureus.43987. eCollection 2023 Aug.

Abstract

Tuberculosis continues to be a big challenge to public health. Isolated cases of tuberculous mediastinal lymphadenopathy in an immunocompetent child without pulmonary involvement are relatively rare. Compared to adults, children are susceptible to such infections; however, due to a lack of specific clinical features and the involvement of invasive techniques in establishing the diagnosis, there are chances of a diagnostic delay. A case of a nine-year-old girl who reported having chest pain for one month is presented. In the absence of the constitutional signs and symptoms of tuberculosis, a diagnosis was confirmed with computed tomography, histopathology, and cartridge-based nucleic acid amplification of samples obtained from endobronchial ultrasound-guided transbronchial needle aspiration. She was put on anti-tuberculous treatment for her weight.

摘要

结核病仍然是公共卫生面临的一大挑战。在免疫功能正常且无肺部受累的儿童中,孤立性结核性纵隔淋巴结肿大病例相对罕见。与成人相比,儿童更容易受到此类感染;然而,由于缺乏特异性临床特征以及在确立诊断时需要采用侵入性技术,存在诊断延迟的可能性。本文介绍了一名9岁女孩的病例,该女孩诉说胸痛1个月。在没有结核病全身症状和体征的情况下,通过计算机断层扫描、组织病理学以及对经支气管超声引导下经支气管针吸活检获取的样本进行基于试剂盒的核酸扩增,确诊了病情。根据她的体重给予了抗结核治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50ef/10516330/ea1a6f8357be/cureus-0015-00000043987-i01.jpg

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