Uchiyama Teruya, Nakamura Tomoki, Nakata Kenta, Adachi Ryohei, Hagi Tomohito, Asanuma Kunihiro, Sudo Akihiro
Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan.
Biomed Rep. 2023 Sep 4;19(4):75. doi: 10.3892/br.2023.1657. eCollection 2023 Oct.
Soft tissue sarcomas (STS) are very rare tumors, accounting for <1% of all malignancies. Leiomyosarcoma (LMS), accounts for 10-20% of STS. Gastric metastasis of LMS is extremely rare, and only a few cases have been reported. In the present report, two clinical cases of LMS with gastric metastasis. In the present cases, the metastases presented as a solitary lesion and was located in the upper body anterior wall in case 1, and body-greater curvature in case 2. It is debatable whether to perform any local treatment for gastric metastasis due to its poor prognosis. However, the progression of metastatic cancer in the stomach can lead to gastric bleeding, abdominal pain, and dysphagia, which may further shorten survival and decrease a patient's quality of life. Therefore, metastasectomy was performed in the present cases. This should be considered if digestive tract symptoms occur during the treatment of LMS.
软组织肉瘤（STS）是非常罕见的肿瘤，占所有恶性肿瘤的比例不到1%。平滑肌肉瘤（LMS）占STS的10%-20%。LMS的胃转移极为罕见，仅有少数病例报道。在本报告中，有两例LMS发生胃转移的临床病例。在本病例中，转移灶表现为单个病灶，病例1位于胃体前壁，病例2位于胃体大弯处。由于胃转移预后较差，是否进行任何局部治疗存在争议。然而，胃内转移性癌的进展可导致胃出血、腹痛和吞咽困难，这可能会进一步缩短生存期并降低患者的生活质量。因此，本病例实施了转移瘤切除术。在LMS治疗期间如果出现消化道症状，应考虑这种治疗方法。
