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高级别软组织肉瘤的胃转移:一种罕见情况并文献复习

Gastric metastasis from high-grade soft tissue sarcoma: a rare occurrence with literature review.

作者信息

Krsteska Blagica, Angelovska Tamara, Zdravkovski Panche, Adem Xhem, Todorova Teodora, Samardziski Milan, Dzambaz Darko, Kostadinova-Kunovska Slavica

机构信息

Faculty of Medicine, Institute of Pathology, University Ss. Cyril and Methodius in Skopje, 50 Divizija No.6, Skopje 1000, Republic of North Macedonia.

University Clinic of Gastroenterohepatology, Mother Teresa No.17, Skopje 1000, Republic of North Macedonia.

出版信息

J Surg Case Rep. 2025 Apr 4;2025(4):rjaf192. doi: 10.1093/jscr/rjaf192. eCollection 2025 Apr.

Abstract

Metastasis of high-grade soft tissue sarcoma to the stomach is an extremely rare occurrence. While sarcomas can spread to distant organs, they most commonly metastasize to the lungs, liver, and bones. We report a unique case of gastric metastasis from a high-grade soft tissue sarcoma, occurring 4 years after the initial diagnosis of fibrosarcoma in the right femoral region. The patient did not undergo adjuvant chemotherapy and developed a large soft tissue metastasis in the left gluteal region 2 years later. After 4 years, he presented with a second soft tissue metastasis and suspected metastatic lung nodules. Symptoms of melena and severe anemia prompted a gastroscopic examination, which revealed gastric metastasis from a high-grade soft tissue sarcoma. Due to severe anemia, a palliative gastric resection was performed. A review of the literature indicates that metastatic leiomyosarcomas are the most frequently reported sarcoma subtype metastasizing to the stomach.

摘要

高级别软组织肉瘤转移至胃部极为罕见。虽然肉瘤可扩散至远处器官,但它们最常转移至肺、肝和骨骼。我们报告了一例独特的高级别软组织肉瘤胃转移病例,发生在右股部纤维肉瘤初次诊断4年后。该患者未接受辅助化疗,2年后在左臀区域出现一个大的软组织转移灶。4年后,他出现了第二个软组织转移灶以及疑似转移的肺结节。黑便和严重贫血症状促使进行胃镜检查,结果显示为高级别软组织肉瘤胃转移。由于严重贫血,进行了姑息性胃切除术。文献回顾表明,转移性平滑肌肉瘤是最常报道的转移至胃部的肉瘤亚型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd83/11969146/33a3c5cddf67/rjaf192f1.jpg

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