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[龟脾脏提取物纯化成分的治疗效果]

[Therapeutic effect of purified components of a turtle spleen extract].

作者信息

Turdyev A A, Usmanov R B, Iukel'son L Ia, Nigmatov Z, Madzhidova D Kh

出版信息

Radiobiologiia. 1986 Sep-Oct;26(5):685-8.

PMID:3774982
Abstract

The administration of a spleen extract of Testudo horsfieldi to mice exposed to lethal radiation of 8 Gy was shown to increase the survival rate and to stimulate haemopoiesis and formation of endocolonies in the spleen. The gel filtration method was used to obtain an active fraction which was subjected to chromatography on cation exchanger to give two more fractions. Active was the fraction with basic components.

摘要

给暴露于8 Gy致死性辐射的小鼠注射印度星龟脾脏提取物,结果显示可提高存活率,并刺激脾脏中的造血作用和内集落形成。采用凝胶过滤法获得活性组分,该活性组分在阳离子交换剂上进行色谱分离,得到另外两个组分。具有碱性成分的组分具有活性。

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