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[在扩散小室中半固体琼脂内形成集落的艾氏腹水癌克隆形成细胞的放射敏感性]

[Radiosensitivity of clonogenic cells of Ehrlich ascites carcinoma forming colonies in semiliquid agar in diffusion chambers].

作者信息

Konopliannikov A G, Shteĭn L V, Kolesnikova A I

出版信息

Radiobiologiia. 1986 Sep-Oct;26(5):688-90.

PMID:3774983
Abstract

A study was made of the dependence of survival of Ehrlich ascites tumor clonogenic cells on the 3d and 7th days following inoculation upon radiation dose (60Co-gamma-rays) delivered under well oxygenated in vitro conditions. No differences were detected in radiosensitivity of 3- and 7-day Ehrlich ascites tumor cells: in both cases, the "dose-effect" curves were S-shaped with a small shoulder and close D0 values.

摘要

研究了艾氏腹水瘤克隆形成细胞在接种后第3天和第7天的存活情况对在体外充分氧合条件下给予的辐射剂量(60Co-γ射线)的依赖性。未检测到接种后3天和7天的艾氏腹水瘤细胞在放射敏感性上的差异:在这两种情况下,“剂量效应”曲线均为小肩峰的S形,且D0值相近。

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