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[低氧条件下经钴60γ射线照射的艾氏腹水癌克隆形成细胞的放射敏感性]

[Radiosensitivity of Ehrlich ascites carcinoma clonogenic cells irradiated with Co60 gamma rays in hypoxic conditions].

作者信息

Konopliannikov A G, Kolesnikova A I, Shteĭn L V

出版信息

Radiobiologiia. 1986 Sep-Oct;26(5):710-2.

PMID:3774989
Abstract

A study was made of the survival rate of Ehrlich ascites clonogenic cells on the 7th day following inoculation depending on 60Co-gamma-radiation dose delivered under hypoxic and oxygenating conditions in vitro. In both cases the survival curves had a small shoulder and an exponential part. The oxygen enhancement ratio determined as a ratio of D0 for hypoxic (6.59 Gy) and oxygenated (2.06 Gy) cells was 3.2.

摘要

一项关于接种后第7天艾氏腹水克隆形成细胞存活率的研究，该存活率取决于体外在缺氧和充氧条件下给予的60Co-γ辐射剂量。在这两种情况下，存活曲线都有一个小的肩部和一个指数部分。以缺氧（6.59 Gy）和充氧（2.06 Gy）细胞的D0比值确定的氧增强比为3.2。

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