[伊多喜酰胺对茶碱代谢的影响]
[Influence of idrocilamide on the metabolism of theophylline].
作者信息
Lacroix C, Nouveau J, Hubscher P, Tardif D, Ray M, Goulle J P
出版信息
Rev Pneumol Clin. 1986;42(3):164-6.
PMID:3775181
Abstract
The pharmacokinetics of theophylline as a sirup (5 or 6 mg . kg-1 bodyweight) were studied in 6 volunteers before and after association with idrocilamide. The results showed an increase in theophylline half-life, a decrease in clearance and a slight decrease in volume of distribution.
摘要
对6名志愿者在联用伊多酰胺前后，研究了糖浆形式的氨茶碱（5或6毫克·千克体重）的药代动力学。结果显示氨茶碱半衰期延长，清除率降低，分布容积略有减小。
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