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遗传性出血性毛细血管扩张症患者的口腔表现和牙科注意事项:范围综述。

Oral manifestations and dental considerations of patients with hereditary hemorrhagic telangiectasia: a scoping review.

机构信息

Department of Plastic and Oral and Maxillofacial Surgery, Uppsala University, Uppsala, Sweden.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2023 Dec;136(6):691-702. doi: 10.1016/j.oooo.2023.08.001. Epub 2023 Aug 9.

DOI:10.1016/j.oooo.2023.08.001
PMID:37752017
Abstract

OBJECTIVE

We examined the range, nature, and extent of research conducted regarding the oral and dental implications of hereditary hemorrhagic telangiectasia (HHT) to identify gaps in the research and knowledge of the field.

STUDY DESIGN

We performed a scoping review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews and 2017 Guidance for the Conduct of Joanna Briggs Institute Scoping Reviews. We searched the MEDLINE and Web of Science databases for all full-text articles published in English from December 1946 to October 2022.

RESULTS

We identified 103 articles describing oral and dental considerations of patients with HHT, primarily case reports. Most reported oral telangiectasias of the tongue, lips, and palate. Many reported management of bleeding and the use or recommendation of prophylactic antibiotics before dental procedures.

CONCLUSIONS

Oral telangiectasias are commonly found in patients with hereditary hemorrhagic telangiectasia, and dental professionals may be the first to diagnose it in their patients. Early detection and diagnosis are important to prevent potentially fatal outcomes, and prophylactic antibiotics before procedures may be warranted.

摘要

目的

我们研究了遗传性出血性毛细血管扩张症(HHT)口腔和牙齿影响的研究范围、性质和程度,以确定该领域研究和知识的空白。

研究设计

我们根据系统评价和荟萃分析扩展的首选报告项目以及 2017 年乔安娜·布里格斯研究所范围评价指南进行了范围审查。我们在 MEDLINE 和 Web of Science 数据库中搜索了 1946 年 12 月至 2022 年 10 月期间发表的所有英文全文文章。

结果

我们确定了 103 篇描述 HHT 患者口腔和牙齿注意事项的文章,主要是病例报告。大多数报告了舌、唇和 palate 的口腔毛细血管扩张症。许多人报告了出血的处理以及在牙科手术前使用或推荐预防性抗生素。

结论

遗传性出血性毛细血管扩张症患者中常见口腔毛细血管扩张症,口腔医生可能是其患者中第一个诊断该病的人。早期发现和诊断对于预防潜在的致命后果很重要,在手术前使用预防性抗生素可能是合理的。

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