Department of Ophthalmology, The Second Hospital of Jilin University, No.218, Ziqiang Street, Nanguan District, Changchun City, Jilin Province, China.
BMC Ophthalmol. 2023 Sep 26;23(1):395. doi: 10.1186/s12886-023-03135-5.
To report the spontaneous regression of an isolated retinal astrocytic hamartoma in a newborn. During the seven-month follow-up duration, fundus photography and fluorescein angiography examinations were performed.
An isolated retinal astrocytic hamartoma was detected in the nasal retina of the left eye of a 4-day-old male infant. At the time of initial presentation, we detected a solitary yellowish-white flat mass with an approximate size of 1.5 disc diameters in the nasal retina. Fluorescein angiography (FA) revealed a diffuse hyperfluorescence with slight fluorescence leakage. Seven months later, the fundus examination showed no lesion in the left eye, FA revealed mild tortuous vessels without leakage.
In the present case, we established that the isolated retinal astrocytic hamartoma in this infant has underwent spontaneous regression. This case can point out that follow -up reexaminations are advisable for a solitary yellowish-white flat mass of the fundus in a newborn.
报告一例新生儿期孤立性视网膜星形细胞瘤的自发消退。在 7 个月的随访期间,进行了眼底照相和荧光素血管造影检查。
一名 4 天大的男性婴儿左眼的鼻侧视网膜发现孤立性视网膜星形细胞瘤。初次就诊时,我们发现鼻侧视网膜有一个约 1.5 个视盘直径大小的孤立性黄白色扁平肿块。荧光素血管造影(FA)显示弥漫性高荧光,有轻微荧光渗漏。7 个月后,左眼眼底检查未见病变,FA 显示轻度扭曲血管,无渗漏。
在本病例中,我们确定该婴儿的孤立性视网膜星形细胞瘤发生了自发消退。该病例提示,对于新生儿眼底的孤立性黄白色扁平肿块,建议进行随访复查。