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麻风病所致的多发性单神经炎:超声与电诊断视角

Mononeuritis Multiplex Due to Hansen's Disease: A Look Through Ultrasound and Electrodiagnosis.

作者信息

Herrera Malpica Wilmer Santiago, Muñetones Hernández Paula Vanessa, Perez Becerra Nathalia Maria, Muñoz Rodriguez Jorge Nicolas, Diaz Ruiz Jorge Arturo

机构信息

Rehabilitation Medicine, Universidad Nacional De Colombia, Bogotá, COL.

General Medicine, Universidad Nacional De Colombia, Bogotá, COL.

出版信息

Cureus. 2023 Aug 26;15(8):e44175. doi: 10.7759/cureus.44175. eCollection 2023 Aug.

DOI:10.7759/cureus.44175
PMID:37753013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10519664/
Abstract

Hansen's disease is caused by Mycobacterium leprae. This bacillus can invade the peripheral nerves asymmetrically, including the ulnar, median, and radial nerves, causing mononeuritis multiplex. We present the case of a 41-year-old man with a history of Hansen's disease with sensory and motor symptoms. Electrodiagnostic studies and ultrasound showed asymmetric lesions of the median, ulnar, and radial nerves. Because this is the main complication of this pathology, electrodiagnosis is clearly valuable for its diagnosis, demonstrating axonal and myelin involvement, as well as signs of denervation and reinnervation. Ultrasound is valuable in the detection, diagnosis, and assessment of the extent of mononeuritis multiplex due to Hansen's disease. It aids in identifying significant inflammatory deterioration, as indicated by increased blood flow in the nerves and enlargement of the nerves. This technique allows for the exploration of nerves such as the ulnar nerve and branches of the brachial plexus. In a complementary way, ultrasound provides information on the severity of the disease. Early diagnosis of this entity is essential because it can generate aesthetic and functional permanent affectation.

摘要

麻风病由麻风分枝杆菌引起。这种杆菌可不对称地侵犯周围神经,包括尺神经、正中神经和桡神经,导致多发性单神经炎。我们报告一例41岁有麻风病史且伴有感觉和运动症状的男性病例。电诊断研究和超声显示正中神经、尺神经和桡神经存在不对称性病变。由于这是该疾病的主要并发症,电诊断对于其诊断显然具有重要价值,可显示轴突和髓鞘受累情况以及失神经和再支配的迹象。超声在检测、诊断和评估麻风病所致多发性单神经炎的范围方面具有重要价值。它有助于识别明显的炎症恶化,表现为神经内血流增加和神经增粗。该技术可用于探查尺神经和臂丛神经分支等神经。作为一种辅助手段,超声可提供有关疾病严重程度的信息。对该疾病进行早期诊断至关重要,因为它可能导致美观和功能方面的永久性损害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/727f/10519664/c6162fbb0e63/cureus-0015-00000044175-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/727f/10519664/9b6e6824269a/cureus-0015-00000044175-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/727f/10519664/c6162fbb0e63/cureus-0015-00000044175-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/727f/10519664/9b6e6824269a/cureus-0015-00000044175-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/727f/10519664/c6162fbb0e63/cureus-0015-00000044175-i02.jpg

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本文引用的文献

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The red flags of ulnar neuropathy in leprosy.麻风病所致尺神经病变的警示征象。
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Sonographic pattern of median nerve enlargement in Hansen's neuropathy.汉森氏神经病变中正中神经增粗的超声表现
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多发性单神经炎作为纯神经炎型麻风的初始表现——一个被遗忘的病因:临床、电诊断及病理相关性
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Ultrasound of the Brachial Plexus.臂丛神经超声检查
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Leprosy neuropathy: clinical presentations.麻风性神经病:临床表现
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Neuromuscular ultrasonography: quantifying muscle and nerve measurements.神经肌肉超声检查:量化肌肉和神经测量值。
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