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病例报告:脊髓炎和神经节炎,麻风病的一种非典型表现。

Case report: Myelitis and ganglionitis, an atypical presentation of Hansen's disease.

作者信息

Spitz Clarissa Neves, Pitta Izabela Jardim R, Andrade Ligia, de Carvalho Larissa Bittencourt, de Carvalho Diogo Matheus Terrana, Schmidt Felipe da Rocha, Siquara de Sousa Ana Caroline, Mendonça Silvana Machado, Sarno Euzenir Nunes, Sales Anna Maria, Pinheiro Roberta Olmo, Jardim Marcia Rodrigues

机构信息

Post-Graduate Program in Neurology, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.

Laboratory of Leprosy, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Front Med (Lausanne). 2024 May 20;11:1400423. doi: 10.3389/fmed.2024.1400423. eCollection 2024.

Abstract

Hansen's disease, or leprosy, is a disease characterized by dermatological and neurological disorders. A neural form also exists, in which peripheral neuropathy occurs in the absence of skin lesions. However, cases of leprosy that involve the central nervous system and proximal nerves are rare in the literature. We describe the case of an oligosymptomatic patient diagnosed with the neural form of leprosy with involvement of peripheral nerves, dorsal root ganglion, and cervical spinal cord in an atypical presentation of the disease. Through complementary examinations and nerve biopsies, the bacillus was identified, and treatment was subsequently initiated. This case highlights the importance of investigating the suspicion of leprosy, even in cases with atypical manifestations, as early diagnosis and treatment can reduce neurological damage and deformities.

摘要

麻风病,又称汉森氏病,是一种以皮肤和神经紊乱为特征的疾病。也存在一种神经型麻风病,其外周神经病变时无皮肤病变。然而,文献中涉及中枢神经系统和近端神经的麻风病病例很少。我们描述了一例症状轻微的患者,该患者被诊断为神经型麻风病,其外周神经、背根神经节和颈脊髓在疾病的非典型表现中受累。通过辅助检查和神经活检,鉴定出了杆菌,随后开始治疗。该病例强调了即使在非典型表现的病例中,对麻风病疑似病例进行调查的重要性,因为早期诊断和治疗可以减少神经损伤和畸形。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c6d/11149418/e4541c1d1ee2/fmed-11-1400423-g001.jpg

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