Bengoa J M, Widgren S
Schweiz Med Wochenschr. 1986 Oct 4;116(40):1358-66.
The gastrointestinal manifestations seen in acquired immune deficiency syndrome (AIDS) are discussed based on the observation of 14 patients with a positive serology for LAV/HTLV III antibody. AIDS was confirmed in 8 cases and AIDS related complex (ARC) in 6 cases. Risk groups included 6 homosexuals, 6 drug abusers and 2 patients from Zaïre. All the AIDS cases underwent gastrointestinal endoscopy and biopsy; in 5 patients a necropsy was performed. Evaluation of the immune status showed lymphopenia and a decreased ratio of OKT4/OKT8. Clinical and pathological observations are discussed sequentially. Acute esophagitis includes cases of Candida albicans super-infection, cytomegalovirus and herpes simplex. Acute enteritis and colitis were seen in association with cryptosporidium, Isospora belli and CMV. 3 cases were found to have chronic duodenitis and malabsorption. Digestive lesions of Kaposi's sarcoma were seen in 3 cases. Diagnosis and treatment of gastrointestinal infections in AIDS is important in view of the high morbidity and serious secondary complications.
基于对14例LAV/HTLV III抗体血清学检测呈阳性患者的观察，对获得性免疫缺陷综合征（AIDS）中出现的胃肠道表现进行了讨论。确诊为AIDS的有8例，艾滋病相关综合征（ARC）的有6例。危险人群包括6名同性恋者、6名药物滥用者和2名来自扎伊尔的患者。所有AIDS病例均接受了胃肠道内镜检查和活检；5例患者进行了尸检。免疫状态评估显示淋巴细胞减少，OKT4/OKT8比值降低。依次讨论临床和病理观察结果。急性食管炎包括白色念珠菌二重感染、巨细胞病毒和单纯疱疹病例。急性肠炎和结肠炎与隐孢子虫、贝氏等孢球虫和巨细胞病毒有关。3例发现有慢性十二指肠炎症和吸收不良。3例可见卡波西肉瘤的消化系病变。鉴于高发病率和严重的继发并发症，AIDS患者胃肠道感染的诊断和治疗很重要。
