Fasoula Nikolina-Alexia, Xie Yi, Katsouli Nikoletta, Reidl Mario, Kallmayer Michael A, Eckstein Hans-Henning, Ntziachristos Vasilis, Hadjileontiadis Leontios, Avgerinos Dimitrios V, Briasoulis Alexandros, Siasos Gerasimos, Hosseini Kaveh, Doulamis Ilias, Kampaktsis Polydoros N, Karlas Angelos
Institute of Biological and Medical Imaging, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Chair of Biological Imaging at the Central Institute for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, 81675 Munich, Germany.
J Cardiovasc Dev Dis. 2023 Sep 6;10(9):383. doi: 10.3390/jcdd10090383.
Microvascular changes in diabetes affect the function of several critical organs, such as the kidneys, heart, brain, eye, and skin, among others. The possibility of detecting such changes early enough in order to take appropriate actions renders the development of appropriate tools and techniques an imperative need. To this end, several sensing and imaging techniques have been developed or employed in the assessment of microangiopathy in patients with diabetes. Herein, we present such techniques; we provide insights into their principles of operation while discussing the characteristics that make them appropriate for such use. Finally, apart from already established techniques, we present novel ones with great translational potential, such as optoacoustic technologies, which are expected to enter clinical practice in the foreseeable future.
糖尿病中的微血管变化会影响多个重要器官的功能，如肾脏、心脏、大脑、眼睛和皮肤等。尽早检测到这些变化以便采取适当行动的可能性使得开发合适的工具和技术成为迫切需求。为此，已经开发或采用了多种传感和成像技术来评估糖尿病患者的微血管病变。在此，我们介绍这些技术；在讨论使其适用于此类用途的特性时，我们深入探讨了它们的工作原理。最后，除了已有的技术外，我们还介绍了具有巨大转化潜力的新技术，如光声技术，预计在可预见的未来这些技术将进入临床实践。
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