Truter P J, Franszen S, van der Merwe J V, Coetzee M J
S Afr Med J. 1986 Oct 25;70(9):557-8.
A case of hydrops fetalis with intra-uterine death after premature closure of the ductus arteriosus because of inhibition of premature labour by the administration of indomethacin is presented. The physiology of acute and chronic intra-uterine constriction of the ductus arteriosus and the effects of indomethacin on the fetal circulation are discussed. Mention is also made of the moral conflict confronting the doctor in the management of an affected fetus during the third trimester.
本文报告1例因使用吲哚美辛抑制早产导致动脉导管过早关闭后发生胎儿水肿并宫内死亡的病例。文中讨论了动脉导管急性和慢性宫内缩窄的生理机制以及吲哚美辛对胎儿循环的影响。此外，还提及了孕晚期医生在处理受影响胎儿时面临的道德冲突。
