Victor Babes Clinical Hospital for Infectious and Tropical Diseases, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
AIDS Res Hum Retroviruses. 2023 Nov;39(11):616-620. doi: 10.1089/AID.2023.0010.
Monkeypox virus (mpox), a double-stranded DNA virus belonging to the Orthopox genus, can affect vulnerable anatomic sites, including the eyes, causing a monkeypox-related ophthalmic disease. The mpox virus may enter the eye via autoinoculation and cause multiple problems from mild lesions including conjunctivitis, blepharitis, keratitis, to severe ones such as corneal ulcers, corneal scarring, and rarely loss of vision. The aim of this article is to aggregate from an ophthalmologic point of view what is presently known about mpox-related ophthalmic disease (mpoxROD) and to present a particular case of a 41-year-old, white, bisexual, HIV positive male, with severe ocular complications. This article presents the first reported case in Romania, of severe mpoxROD, with clinically relevant information for infectious disease doctors and especially for ophthalmologists.
猴痘病毒（mpox）是一种双链 DNA 病毒，属于正痘病毒属，可影响脆弱的解剖部位，包括眼睛，导致与猴痘相关的眼部疾病。mpox 病毒可能通过自身接种进入眼睛，并引起多种问题，从轻度病变，包括结膜炎、睑缘炎、角膜炎，到严重病变，如角膜溃疡、角膜瘢痕，甚至罕见的视力丧失。本文的目的是从眼科角度综合了解目前已知的与猴痘相关的眼部疾病（mpoxROD），并介绍一例 41 岁的白人、双性恋、HIV 阳性男性的严重眼部并发症。本文报道了首例在罗马尼亚发生的严重 mpoxROD 病例，为传染病医生，特别是眼科医生提供了具有临床意义的信息。
