Bode U, Diehl M, Köster B
Strahlenther Onkol. 1986 Oct;162(10):618-20.
The sudden occurrence of an encephalopathic symptomatology within a day following commencement of radiotherapy is demonstrated by a case report of a small child suffering from CNS leukemia. Former intrathecal chemotherapy appears to be a prerequisite for this toxicity. In spite of diuretic therapy the patients condition may worsen initially, but recovery is possible within days. Patient characteristics and disease course identify a new toxicity syndrome, which is not yet familiar.
