Metz O
Kinderarztl Prax. 1981 Feb;49(2):57-64.
It is suggested that cranial computerized (axial) tomography permits a more complete neurologic work-up for all children with acute leukemia. It also permits a better knowledge of the frequency and varieties of cerebral complications in leukemia. Endocranial complications in acute leukemia are essentially infiltrative, hemorrhagic, infectious or iatrogenic. Cranial computerized tomography can demonstrate cerebral changes in meningeal leukemia, hemorrhages, calcifications, brain atrophy or leukencephalopathy. The preliminary results of cranial computerized tomography in childhood leukemia suggest that the iatrogenic main lesion of the brain due to combined radiation-chemotherapy is atrophy whereas that of the intrathecal cytostatic therapy is demyelination. Accurate diagnostics and control of possible cerebral complications in therapy of leukemia is essentially for appropriate therapeutic management. For that cranial computerized tomography may be the best method to a effective exploration of the brain.
有人认为，对于所有急性白血病患儿，头颅计算机断层扫描（轴向扫描）能进行更全面的神经系统检查。它还能让人们更好地了解白血病脑部并发症的发生率和种类。急性白血病的颅内并发症主要为浸润性、出血性、感染性或医源性。头颅计算机断层扫描可显示脑膜白血病、出血、钙化、脑萎缩或白质脑病的脑部变化。儿童白血病头颅计算机断层扫描的初步结果表明，联合放疗化疗导致的脑部医源性主要病变是萎缩，而鞘内细胞毒性治疗导致的是脱髓鞘。在白血病治疗中，准确诊断和控制可能的脑部并发症对于适当的治疗管理至关重要。为此，头颅计算机断层扫描可能是有效探查脑部的最佳方法。
