Funakoshi N, Ohno T, Kanoh T, Uchino H, Miyake T, Oda T, Kiyoshige K, Ishida T, Kohriyama K
Tohoku J Exp Med. 1986 Aug;149(4):359-65. doi: 10.1620/tjem.149.359.
A case of common variable immunodeficiency in a pregnant woman is presented. Lobar pneumonia developed in the sixth month of the pregnancy and her serum immunoglobulin levels were found to be extremely low. She was treated successfully with immune human serum globulin and antibiotics. She delivered a full-term baby without any troubles. Various immunologic studies were done in the peripheral blood of the patient and the neonate. Consequently, functional abnormalities of helper T cells were considered to be responsible for the hypogammaglobulinemia.
本文报告一例孕妇常见可变免疫缺陷病例。该孕妇在妊娠第六个月发生大叶性肺炎，血清免疫球蛋白水平极低。她接受了免疫人血清球蛋白和抗生素治疗，治疗成功。她顺利产下一名足月婴儿。对患者及其新生儿的外周血进行了多项免疫学研究。结果认为辅助性T细胞功能异常是导致低丙种球蛋白血症的原因。
