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2 型糖尿病患者慢性便秘及其相关因素的多中心横断面研究。

Chronic constipation and its associated factors in patients with type-2 diabetes: A multicenter cross-sectional study.

机构信息

Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Ethiopia.

Department of Human Physiology, University of Gondar, Ethiopia.

出版信息

Diabetes Res Clin Pract. 2023 Oct;204:110905. doi: 10.1016/j.diabres.2023.110905. Epub 2023 Sep 25.

DOI:10.1016/j.diabres.2023.110905
PMID:37757985
Abstract

INTRODUCTION

Diabetes is one of the global public health concern and constipation is frequently seen among gastrointestinal symptoms in diabetes. Despite the fact that constipation is common, doctors and/or patients disregard it. This study aimed to determine the prevalence and contributing factors of constipation in patients with diabetes.

METHODS

Multi-center cross-sectional study was carried out and the data was analyzed using STATA 14. Binary and multilevel logistic regressions were also carried out to identify associated to factors. Factors having a p-value of less than 0.05 were deemed statistically significant in the final model.

RESULTS

206 diabetics participated in the survey. The mean age of the participants was 52.7 years (SD ± 11.9). The prevalence of constipation was 16% (95% CI: 10.97-21.07). Age (AOR = 13.56; 95% CI: 1.71, 107.21), females (AOR = 4.58; 95% CI: 1.76, 11.87), the duration of the diabetes (AOR = 3.16; 95% CI: 1.21, 8.24), and psychological distress (AOR = 12.49, 95% CI: 1.53, 101.8) were significant factors.

CONCLUSION

The magnitude of constipation was considerable, and it was linked to psychological distress, longer-lasting diabetes, being a woman, and ageing. Patients with type-2 diabetes need to receive careful treatment in order to reduce the severity of the condition and its additional complications.

摘要

引言

糖尿病是全球公共卫生关注的问题之一,而便秘是糖尿病患者常见的胃肠道症状之一。尽管便秘很常见,但医生和/或患者往往会忽视它。本研究旨在确定糖尿病患者便秘的患病率和相关因素。

方法

进行了一项多中心横断面研究,使用 STATA 14 分析数据。还进行了二项和多水平逻辑回归分析,以确定相关因素。最终模型中具有 p 值小于 0.05 的因素被认为具有统计学意义。

结果

共有 206 名糖尿病患者参与了调查。参与者的平均年龄为 52.7 岁(标准差 ± 11.9)。便秘的患病率为 16%(95%可信区间:10.97-21.07)。年龄(AOR=13.56;95%可信区间:1.71, 107.21)、女性(AOR=4.58;95%可信区间:1.76, 11.87)、糖尿病病程(AOR=3.16;95%可信区间:1.21, 8.24)和心理困扰(AOR=12.49, 95%可信区间:1.53, 101.8)是显著因素。

结论

便秘的程度相当大,与心理困扰、病程较长、女性和年龄有关。需要对 2 型糖尿病患者进行仔细治疗,以减轻病情的严重程度和其并发症。

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